Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NLRP3 | Q96P20 | 4/20 | 0.55 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.46 |
| ▸ | BACE1 | P56817 | 2/20 | 0.43 |
| ▸ | NCF1 | P14598 | 2/20 | 0.43 |
| ▸ | NOS2 | P35228 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.42 |
| ▸ | MPO | P05164 | 2/20 | 0.41 |
| ▸ | LRRK2 | Q5S007 | 1/20 | 0.39 |
| ▸ | LCK | P06239 | 1/20 | 0.39 |
| ▸ | KIT | P10721 | 1/20 | 0.39 |
| ▸ | SRC | P12931 | 1/20 | 0.39 |
| ▸ | KDR | P35968 | 1/20 | 0.39 |
| ▸ | ADORA2A | P29274 | 2/20 | 0.39 |
| ▸ | ADORA1 | P30542 | 2/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30437851 | 0.79 | CHRNA7 (0.49) | NLRP3NOTUMKDM4EALDH1A1MAPK1 | |
| SCHEMBL20641982 | 0.78 | NLRP3 (0.62) | NLRP3NOTUMBACE1KDM4EALDH1A1 | |
| SCHEMBL30437703 | 0.78 | NLRP3 (0.62) | NLRP3NOTUMBACE1KDM4EALDH1A1 | |
| SCHEMBL20651722 | 0.75 | NLRP3 (0.76) | NLRP3NOTUMKDM4EALDH1A1MAPK1 | |
| SCHEMBL3665773 | 0.74 | NOTUM (0.53) | NLRP3NOTUMKDM4EALDH1A1MAPK1 | |
| SCHEMBL5337022 | 0.74 | NOTUM (0.53) | NLRP3NOTUMKDM4EALDH1A1MAPK1 | |
| SCHEMBL20641899 | 0.74 | NLRP3 (0.71) | NLRP3NOTUMKDM4EALDH1A1MAPK1 | |
| SCHEMBL3974447 | 0.73 | HRH3 (0.53) | NLRP3NOTUMKDM4EALDH1A1MAPK1 | |
| SCHEMBL29614982 | 0.73 | NOTUM (0.52) | NLRP3NOTUMKDM4EALDH1A1MAPK1 | |
| SCHEMBL17743393 | 0.73 | NOTUM (0.52) | NLRP3NOTUMKDM4EALDH1A1MAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111793060-B | NLRP3 modulators | 先天肿瘤免疫公司 | 2023-06-06 | — | — | CN | disclosed |