Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | APP | P05067 | 14/20 | 0.65 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.61 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.40 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | NPC1 | O15118 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | HPGD | P15428 | 2/20 | 0.40 |
| ▸ | RAB9A | P51151 | 2/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | CRHBP | P24387 | 1/20 | 0.37 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.37 |
| ▸ | CA12 | O43570 | 2/20 | 0.36 |
| ▸ | POLB | P06746 | 2/20 | 0.36 |
| ▸ | CA9 | Q16790 | 2/20 | 0.36 |
| ▸ | GLA | P06280 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | GBA1 | P04062 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3974521 | 0.85 | APP (0.72) | APPCYP1A2KDM4EALDH1A1HPGD | |
| SCHEMBL18653522 | 0.84 | APP (0.70) | APPCYP1A2KDM4EKMT2AMEN1 | |
| SCHEMBL21211676 | 0.82 | APP (0.70) | APPCYP1A2KDM4EKMT2AMEN1 | |
| SCHEMBL19627052 | 0.82 | APP (0.64) | APPCYP1A2KDM4EKMT2AMEN1 | |
| SCHEMBL18932158 | 0.81 | APP (0.74) | APPCYP1A2KDM4EKMT2AMEN1 | |
| SCHEMBL24179877 | 0.81 | APP (0.72) | APPCYP1A2ALDH1A1HPGDCA12 | |
| SCHEMBL12189748 | 0.80 | APP (0.67) | APPCYP1A2KDM4EKMT2AMEN1 | |
| SCHEMBL10038463 | 0.79 | APP (0.75) | APPCYP1A2KDM4EKMT2AMEN1 | |
| SCHEMBL563392 | 0.79 | APP (1.00) | APPCYP1A2KDM4ENPC1ALDH1A1 | |
| SCHEMBL31115697 | 0.79 | APP (1.00) | APPCYP1A2KDM4ENPC1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9506929-B2 | Selective detection of amino group containing thiols | PORTLAND STATE UNIVERSITY (US) | 2016-11-29 | — | — | US | disclosed |
| US-9506929-B2 | Selective detection of amino group containing thiols | PORTLAND STATE UNIVERSITY (US) | 2016-11-29 | — | — | US | disclosed |
| US-20150010938-A1 | SELECTIVE DETECTION OF THIOLS | OREGON STATE BOARD OF HIGHER EDUCATION ON BEHALF OF PORTLAND STATE UNIVERSITY (US) | 2015-01-08 | — | — | US | disclosed |
| US-20150010938-A1 | SELECTIVE DETECTION OF THIOLS | OREGON STATE BOARD OF HIGHER EDUCATION ON BEHALF OF PORTLAND STATE UNIVERSITY (US) | 2015-01-08 | — | — | US | disclosed |
| WO-2013126816-A1 | SELECTIVE DETECTION OF THIOLS | OREGON STATE BOARD OF HIGHER EDUCATION ON BEHALF OF PORTLAND STATE UNIVERSITY (US) | 2013-08-29 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20150010938-A1 | SELECTIVE DETECTION OF THIOLS | CBS, CTH, GSTM2 | APP 2544/4885CYP1A2 1062/4885KDM4E 4336/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.