SCHEMBL397469

SCHEMBL397469

C=C(C)C(=O)Nc1ccc(NS(=O)(=O)c2ccccc2)cc1

nearest known ligand 0.72

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 6/20 0.61
KMT2A Q03164 6/20 0.61
GAA P10253 1/20 0.61
GFER P55789 1/20 0.61
ALDH1A1 P00352 3/20 0.57
PKM P14618 1/20 0.57
KEAP1 Q14145 2/20 0.56
IL1RN P18510 1/20 0.56
ERAP1 Q9NZ08 1/20 0.56
HDAC1 Q13547 3/20 0.56
CA12 O43570 2/20 0.55
CA9 Q16790 2/20 0.55
NR1I2 O75469 1/20 0.54
HDAC8 Q9BY41 2/20 0.53
HDAC3 O15379 1/20 0.53
HDAC4 P56524 1/20 0.53
HDAC7 Q8WUI4 1/20 0.53
HDAC2 Q92769 1/20 0.53
HDAC10 Q969S8 1/20 0.53
HDAC11 Q96DB2 1/20 0.53

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL396617 0.95 MEN1 (0.68) MEN1KMT2AGAAGFERALDH1A1
SCHEMBL7785812 0.88 IDO1 (0.51) MEN1KMT2AGAAGFERALDH1A1
SCHEMBL396170 0.87 TDP1 (0.56) MEN1KMT2AGAAGFERALDH1A1
SCHEMBL396104 0.87 TDP1 (0.56) MEN1KMT2AGAAGFERALDH1A1
SCHEMBL395032 0.87 ALDH1A1 (0.64) MEN1KMT2AGAAGFERALDH1A1
SCHEMBL9978102 0.86 MEN1 (0.59) MEN1KMT2AGAAGFERALDH1A1
SCHEMBL8862316 0.86 MEN1 (0.50) MEN1KMT2AGAAGFERALDH1A1
SCHEMBL9887823 0.85 CA1 (0.67) MEN1KMT2AALDH1A1CA12CA9
SCHEMBL11700730 0.84 MEN1 (0.82) MEN1KMT2AGAAGFERALDH1A1
SCHEMBL397717 0.84 SMN1; SMN2 (0.61) MEN1KMT2AGAAALDH1A1PKM

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 33 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5141838-A Lithography printing plates FUJI PHOTO FILM CO., LTD. (JP) 1992-08-25 US claimed
US-9738064-B2 Lithographic printing plate precursor AGFA GRAPHICS N.V. (BE) 2017-08-22 US disclosed
EP-2668039-B1 A LITHOGRAPHIC PRINTING PLATE PRECURSOR AGFA GRAPHICS NV (BE) 2015-06-03 EP disclosed
US-9029066-B2 Lithographic printing plate precursor AGFA GRAPHICS NV (BE) 2015-05-12 US disclosed
US-8978554-B2 Alkali soluble resin AGFA GRAPHICS N.V. (BE) 2015-03-17 US disclosed
US-8771918-B2 Lithographic printing plate precursor AGFA GRAPHICS N.V. (BE) 2014-07-08 US disclosed
US-20130298792-A1 LITHOGRAPHIC PRINTING PLATE PRECURSOR AGFA GRAPHICS NV (BE) 2013-11-14 US disclosed
US-20120266768-A1 Lithographic Printing Plate Precursor AGFA GRAPHICS NV (BE) 2012-10-25 US disclosed
EP-2489512-A1 A lithographic printing plate precursor Agfa Graphics N.V. (BE) 2012-08-22 EP disclosed
US-20120146264-A1 RESIN COMPOSITION FOR LASER ENGRAVING, RELIEF PRINTING PLATE PRECURSOR FOR LASER ENGRAVING AND PROCESS FOR PRODUCING SAME, AND PROCESS FOR MAKING RELIEF PRINTING PLATE FUJIFILM CORPORATION (JP) 2012-06-14 US disclosed
US-6517987-B2 Mixture of 1,2-naphthoquinone-2-diazide-5-sulfonic acid and polymer FUJI PHOTO FILM CO., LTD. (JP) 2003-02-11 US disclosed
US-20010041299-A1 Positive-working presensitized plate useful for preparing a lithographic printing plate FUJIFILM CORPORATION (JP) 2001-11-15 US disclosed
EP-0671660-B1 Lead-frame forming material FUJI PHOTO FILM CO LTD (JP) 2001-10-17 EP disclosed
EP-1136886-A1 Positive-working presensitized plate useful for preparing a lithographic printing plate Fuji Photo Film Co., Ltd. (JP) 2001-09-26 EP disclosed
CN-1314617-A Positive sensitive flat-plate printing plate FUJI PHOTO FILM CO LTD (JP) 2001-09-26 CN disclosed
EP-1077392-A1 Photosensitive lithographic printing plate FUJI PHOTO FILM CO., LTD. (JP) 2001-02-21 EP disclosed
EP-0330239-B1 Photosensitive composition FUJI PHOTO FILM CO LTD (JP) 1996-05-22 EP disclosed
EP-0671660-A2 Lead-frame forming material FUJI PHOTO FILM CO., LTD. (JP) 1995-09-13 EP disclosed
US-5141838-A Lithography printing plates FUJI PHOTO FILM CO., LTD. (JP) 1992-08-25 US disclosed
EP-0330239-A2 Photosensitive composition FUJI PHOTO FILM CO., LTD. (JP) 1989-08-30 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20120146264-A1 RESIN COMPOSITION FOR LASER ENGRAVING, RELIEF PRINTING PLATE PRECURSOR FOR LASER ENGRAVING AND PROCESS FOR PRODUCING SAME, AND PROCESS FOR MAKING RELIEF PRINTING PLATE EIF3L, EIF2B1, EIF2B5 MEN1 3535/4885KMT2A 506/4885GAA 3206/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.