Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A2 | P23975 | 20/20 | 0.90 |
| ▸ | SLC6A3 | Q01959 | 8/20 | 0.68 |
| ▸ | SLC6A4 | P31645 | 6/20 | 0.68 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL3978358 | 0.99 | SLC6A2 (0.93) | SLC6A2SLC6A3SLC6A4 | |
| SCHEMBL4627427 | 0.88 | SLC6A2 (0.71) | SLC6A2SLC6A3SLC6A4 | |
| Hydrochloric Acid SCHEMBL3952528 | 0.87 | SLC6A2 (0.73) | SLC6A2SLC6A3SLC6A4 | |
| SCHEMBL3978146 | 0.86 | SLC6A2 (0.90) | SLC6A2SLC6A3SLC6A4 | |
| SCHEMBL3973718 | 0.86 | SLC6A2 (0.69) | SLC6A2SLC6A3SLC6A4 | |
| Hydrochloric Acid SCHEMBL3979011 | 0.85 | SLC6A2 (0.93) | SLC6A2SLC6A3SLC6A4 | |
| Hydrochloric Acid SCHEMBL3975365 | 0.85 | SLC6A2 (0.71) | SLC6A2SLC6A3SLC6A4 | |
| SCHEMBL4626016 | 0.85 | SLC6A2 (0.67) | SLC6A2SLC6A3SLC6A4 | |
| SCHEMBL4626050 | 0.85 | SLC6A2 (0.72) | SLC6A2SLC6A3SLC6A4 | |
| SCHEMBL3972448 | 0.85 | SLC6A2 (0.93) | SLC6A2SLC6A3SLC6A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1894227-A | Phenylpiperazine cycloalkanol derivatives and methods of their use | WYETH CORP (US) | 2007-01-10 | — | — | CN | claimed |
| EP-1673358-A1 | PHENYLPIPERAZINE CYCLOALKANOL DERIVATIVES AND METHODS OF THEIR USE | Wyeth (US) | 2006-06-28 | — | — | EP | claimed |
| US-20050143394-A1 | Phenylpiperazine cycloalkanol derivatives and methods of their use | WYETH (US) | 2005-06-30 | — | — | US | claimed |
| WO-2005037808-A1 | PHENYLPIPERAZINE CYCLOALKANOL DERIVATIVES AND METHODS OF THEIR USE | WYETH (US) | 2005-04-28 | — | — | WO | claimed |
| US-7531543-B2 | Phenylpiperazine cycloalkanol derivatives and methods of their use | WYETH (US) | 2009-05-12 | — | — | US | disclosed |
| CN-1894227-A | Phenylpiperazine cycloalkanol derivatives and methods of their use | WYETH CORP (US) | 2007-01-10 | — | — | CN | disclosed |
| US-20050143394-A1 | Phenylpiperazine cycloalkanol derivatives and methods of their use | WYETH (US) | 2005-06-30 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050143394-A1 | Phenylpiperazine cycloalkanol derivatives and methods of their use | HTR5A, PNMT, HTR3A | SLC6A2 49/4885SLC6A3 100/4885SLC6A4 56/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.