Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.48 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.48 |
| ▸ | GAA | P10253 | 4/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.46 |
| ▸ | MAPT | P10636 | 3/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.46 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.46 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.46 |
| ▸ | HPGD | P15428 | 2/20 | 0.43 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | CA1 | P00915 | 2/20 | 0.39 |
| ▸ | CA2 | P00918 | 2/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3977164 | 0.85 | ALDH1A1 (0.49) | ALDH1A1GAASMN1; SMN2MAPTLMNA | |
| SCHEMBL2384740 | 0.77 | CNR2 (0.41) | ALDH1A1SMN1; SMN2LMNANPC1RAB9A | |
| SCHEMBL14129389 | 0.71 | ALDH1A1 (0.57) | ALDH1A1L3MBTL1GAASMN1; SMN2MAPT | |
| SCHEMBL185475 | 0.71 | PPARG (0.42) | ALDH1A1SMN1; SMN2LMNA | |
| SCHEMBL5238900 | 0.70 | BACE1 (0.43) | ALDH1A1SMN1; SMN2CYP1A2CYP2C9CYP2C19 | |
| SCHEMBL2585606 | 0.70 | ALDH1A1 (0.71) | ALDH1A1L3MBTL1GAASMN1; SMN2MAPT | |
| SCHEMBL3976209 | 0.70 | HSD17B10 (0.40) | ALDH1A1SMN1; SMN2LMNACA1CA2 | |
| SCHEMBL4055745 | 0.69 | ALDH1A1 (0.48) | ALDH1A1L3MBTL1GAASMN1; SMN2MAPT | |
| SCHEMBL2590098 | 0.69 | CYP1A2 (0.64) | ALDH1A1L3MBTL1GAASMN1; SMN2MAPT | |
| SCHEMBL13886030 | 0.68 | ALDH1A1 (0.54) | ALDH1A1L3MBTL1GAASMN1; SMN2MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009053448-A1 | COMPOUNDS WHICH POTENTIATE AMPA RECEPTOR AND USES THEREOF IN MEDICINE | GLAXO GROUP LIMITED (GB) | 2009-04-30 | — | — | WO | disclosed |