SCHEMBL397529

SCHEMBL397529

Cc1ccc2ccccc2c1N1C(=O)C=CC1=O

nearest known ligand 0.52

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
TSHR P16473 3/20 0.52
CYP2A6 P11509 3/20 0.52
CYP1A2 P05177 1/20 0.52
MGLL Q99685 3/20 0.47
HCAR1 Q9BXC0 3/20 0.46
HSP90AA1 P07900 1/20 0.44
ALDH1A1 P00352 3/20 0.41
TLR9 Q9NR96 1/20 0.41
HSD17B10 Q99714 2/20 0.40
MAPT P10636 1/20 0.40
PKM P14618 1/20 0.40
HPGD P15428 1/20 0.40
KMT2A Q03164 1/20 0.39
PAX8 Q06710 1/20 0.38
TDP1 Q9NUW8 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29364961 1.00 TSHR (0.52) TSHRCYP2A6CYP1A2MGLLHCAR1
SCHEMBL28278221 0.84 HCAR1 (0.39) TSHRCYP2A6CYP1A2MGLLHCAR1
SCHEMBL28883431 0.82 TSHR (0.47) TSHRCYP2A6CYP1A2HCAR1ALDH1A1
SCHEMBL28883319 0.80 TSHR (0.46) TSHRCYP2A6CYP1A2HCAR1ALDH1A1
SCHEMBL31179986 0.80 TLR9 (0.52) TSHRCYP2A6CYP1A2MGLLHSP90AA1
SCHEMBL21826723 0.80 TLR9 (0.52) TSHRCYP2A6CYP1A2MGLLHSP90AA1
SCHEMBL28883370 0.79 MGLL (0.51) TSHRCYP2A6CYP1A2MGLLHSP90AA1
SCHEMBL28883344 0.79 TSHR (0.44) TSHRCYP2A6CYP1A2HCAR1ALDH1A1
SCHEMBL28883495 0.79 PTPN22 (0.47) CYP1A2MGLLHSP90AA1ALDH1A1TLR9
SCHEMBL11882233 0.79 HSP90AA1 (0.44) TSHRCYP2A6MGLLHCAR1HSP90AA1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 856 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12391729-B2 Fusion proteins, recombinant bacteria, and methods for using recombinant bacteria SPOGEN BIOTECH INC. (US) 2025-08-19 US claimed
US-20240199709-A1 FUSION PROTEINS, RECOMBINANT BACTERIA, AND METHODS FOR USING RECOMBINANT BACTERIA SPOGEN BIOTECH INC (US) 2024-06-20 US claimed
US-11905315-B2 Fusion proteins, recombinant bacteria, and methods for using recombinant bacteria SPOGEN BIOTECH INC. (US) 2024-02-20 US claimed
CN-115340483-A Naphthyl pyrrolindione compound, preparation method and application thereof 南京吉星生物技术开发有限公司 2022-11-15 CN claimed
US-20210179672-A1 FUSION PROTEINS, RECOMBINANT BACTERIA, AND METHODS FOR USING RECOMBINANT BACTERIA GENISYS CREDIT UNION 2021-06-17 US claimed
EP-2533633-B1 FUNGICIDAL MIXTURES LANXESS DISTRIB GMBH (DE) 2017-02-01 EP claimed
WO-2016044655-A2 FUSION PROTEINS, RECOMBINANT BACTERIA, AND METHODS FOR USING RECOMBINANT BACTERIA SPOGEN BIOTECH INC. (US) 2016-03-24 WO claimed
US-20130195997-A1 FUNGICIDAL MIXTURES LANXESS DISTRIBUTION GMBH (DE) 2013-08-01 US claimed
EP-2460408-A1 Nematicidal compositions deVGen N.V. (BE) 2012-06-06 EP claimed
US-20110319435-A1 FUNGICIDE MIXTURES LANXESS DISTRIBUTION GMBH (DE) 2011-12-29 US claimed
US-4649078-A Antimicrobials impregnated into fibers MORTON THIOKOL, INC. (US) 1987-03-10 US claimed
US-4643920-A USING EXHAUSTION BATH MORTON THIOKOL INC. (US) 1987-02-17 US claimed
US-4624677-A Method for controlling antimicrobial content of fibers MORTON THIOKOL, INC. (US) 1986-11-25 US claimed
EP-0197631-A2 Dry blend concentrate of solid biocide and thermoplastic resin powder and method for its preparation MORTON INTERNATIONAL, INC. (US) 1986-10-15 EP claimed
EP-0168949-A1 Microbiocidal compositions and processes for imparting microbiocidal properties to polymer compositions MORTON THIOKOL, INC. (US) 1986-01-22 EP claimed
US-4307109-A COATING OF N-(2-METHYL-1-NAPHTHYL) MALEIMIDE - AMINE CHELATE BACTERICIDE OR FUNGICIDES ABBOTT LABORATORIES (US) 1981-12-22 US claimed
US-4276090-A BITUMEN HEATED BY MICROWAVES ABBOTT LABORATORIES (US) 1981-06-30 US claimed
US-4217282-A Process for making N-(2-methyl-1-naphthyl)-maleimide ABBOTT LABORATORIES (US) 1980-08-12 US claimed
US-4180508-A FUNGICIDES, BACTERICIDES ABBOTT LABORATORIES (US) 1979-12-25 US claimed
US-4141905-A BACTERICIDES, FUNGICIDES ABBOTT LABORATORIES (US) 1979-02-27 US claimed