Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MGLL | Q99685 | 5/20 | 0.51 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.42 |
| ▸ | ELANE | P08246 | 1/20 | 0.40 |
| ▸ | TLR9 | Q9NR96 | 1/20 | 0.38 |
| ▸ | ATM | Q13315 | 1/20 | 0.38 |
| ▸ | NPEPPS | P55786 | 2/20 | 0.37 |
| ▸ | CYP2A6 | P11509 | 2/20 | 0.36 |
| ▸ | TSHR | P16473 | 2/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | THRB | P10828 | 1/20 | 0.35 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28883447 | 0.89 | MGLL (0.44) | MGLLHSP90AA1ELANETLR9ATM | |
| SCHEMBL28883341 | 0.80 | ELANE (0.35) | MGLLELANEATMNPEPPSCYP2A6 | |
| SCHEMBL29364961 | 0.79 | TSHR (0.52) | MGLLHSP90AA1TLR9CYP2A6TSHR | |
| SCHEMBL397529 | 0.79 | TSHR (0.52) | MGLLHSP90AA1TLR9CYP2A6TSHR | |
| SCHEMBL28883382 | 0.78 | ALDH1A1 (0.44) | MGLLTSHRALDH1A1HSD17B10TDP1 | |
| SCHEMBL21826723 | 0.77 | TLR9 (0.52) | MGLLHSP90AA1TLR9ATMCYP2A6 | |
| SCHEMBL31179986 | 0.77 | TLR9 (0.52) | MGLLHSP90AA1TLR9ATMCYP2A6 | |
| SCHEMBL28883479 | 0.76 | MGLL (0.44) | MGLLTLR9NPEPPSLMNATHRB | |
| SCHEMBL28883321 | 0.76 | MGLL (0.44) | MGLLNPEPPSCYP2A6CYP1A2ALDH1A1 | |
| SCHEMBL331144 | 0.76 | MGLL (0.64) | MGLLHSP90AA1TLR9NPEPPS |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115340483-A | Naphthyl pyrrolindione compound, preparation method and application thereof | 南京吉星生物技术开发有限公司 | 2022-11-15 | — | — | CN | claimed |
| CN-115340483-A | Naphthyl pyrrolindione compound, preparation method and application thereof | 南京吉星生物技术开发有限公司 | 2022-11-15 | — | — | CN | disclosed |