Known targets — ChEMBL curated mechanism
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
The experimentally established mechanism targets of Sulfuric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A3 known ✓ | Q01959 | 2/20 | 0.40 |
| ▸ | CHRM2 known ✓ | P08172 | 1/20 | 0.40 |
| ▸ | CHRM1 known ✓ | P11229 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.49 |
| ▸ | HTT | P42858 | 1/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.49 |
| ▸ | DRD2 | P14416 | 2/20 | 0.40 |
| ▸ | DRD4 | P21917 | 2/20 | 0.40 |
| ▸ | DRD3 | P35462 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9518405 | 0.90 | LMNA (0.57) | LMNAHTTKMT2ADRD2DRD4 | |
| Sulfuric Acid SCHEMBL28066027 | 0.88 | PIK3CD (0.42) | DRD2DRD4DRD3SLC6A3 | |
| SCHEMBL8082731 | 0.81 | LMNA (0.44) | LMNAHTTKMT2ACHRM2CHRM1 | |
| SCHEMBL28888490 | 0.81 | DRD2 (0.40) | DRD2DRD4DRD3SLC6A3 | |
| SCHEMBL28524494 | 0.81 | LMNA (0.45) | LMNAHTTKMT2ACHRM2CHRM1 | |
| SCHEMBL4259360 | 0.79 | HTT (0.50) | LMNAHTTKMT2ACHRM2CHRM1 | |
| SCHEMBL22014461 | 0.79 | DRD2 (0.39) | DRD2DRD4DRD3SLC6A3 | |
| SCHEMBL9800977 | 0.79 | LMNA (0.44) | LMNAHTTKMT2ADRD2DRD4 | |
| SCHEMBL22637686 | 0.78 | LMNA (0.49) | LMNAHTTKMT2ACHRM2CHRM1 | |
| Isopropyl Alcohol SCHEMBL7567318 | 0.78 | KMT2A (0.41) | LMNAHTTKMT2ACHRM2CHRM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009058997-A2 | NON-INVASIVE ISOLATION OF FETAL NUCLEIC ACID | BIOCEPT INC. (US) | 2009-05-07 | — | — | WO | claimed |
| WO-2009058997-A2 | NON-INVASIVE ISOLATION OF FETAL NUCLEIC ACID | BIOCEPT INC. (US) | 2009-05-07 | — | — | WO | disclosed |