2-Carboxybenzeneacetic Acid

2-Carboxybenzeneacetic Acid

SCHEMBL3975685

N.O=C(O)Cc1ccccc1C(=O)O

nearest known ligand 0.59

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
BCAT2 O15382 1/20 0.59
AKR1B1 P15121 2/20 0.59
FOLH1 Q04609 2/20 0.57
ALDH1A1 P00352 4/20 0.54
ALOX15 P16050 1/20 0.54
TDP1 Q9NUW8 1/20 0.52
TSHR P16473 1/20 0.52
KDM4E B2RXH2 2/20 0.48
CYP1A2 P05177 2/20 0.48
MAPT P10636 2/20 0.48
CA12 O43570 1/20 0.46
CA1 P00915 1/20 0.46
CA2 P00918 1/20 0.46
HMGB1 P09429 1/20 0.46
HPGD P15428 1/20 0.46
CA4 P22748 1/20 0.46
CA6 P23280 1/20 0.46
CA7 P43166 1/20 0.46
SMN1; SMN2 Q16637 1/20 0.46
CA9 Q16790 1/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
2-Carboxybenzeneacetic Acid SCHEMBL1891118 0.98 AKR1B1 (0.61) BCAT2AKR1B1FOLH1ALDH1A1ALOX15
2-Carboxybenzeneacetic Acid SCHEMBL27477 0.98 AKR1B1 (0.61) BCAT2AKR1B1FOLH1ALDH1A1ALOX15
2-Carboxybenzeneacetic Acid SCHEMBL4828304 0.96 BCAT2 (0.59) BCAT2AKR1B1FOLH1ALDH1A1ALOX15
2-Carboxybenzeneacetic Acid SCHEMBL2148321 0.88 BCAT2 (0.53) BCAT2AKR1B1FOLH1ALDH1A1ALOX15
SCHEMBL8696228 0.86 TSHR (0.56) BCAT2AKR1B1FOLH1ALDH1A1ALOX15
SCHEMBL6530167 0.84 FOLH1 (0.59) BCAT2AKR1B1FOLH1ALDH1A1ALOX15
SCHEMBL11443185 0.83 FOLH1 (0.57) BCAT2AKR1B1FOLH1ALDH1A1ALOX15
Salicylic Acid SCHEMBL8092425 0.82 AKR1B1 (0.77) BCAT2AKR1B1FOLH1ALDH1A1ALOX15
SCHEMBL29410826 0.81 AKR1B1 (0.76) BCAT2AKR1B1TDP1TSHRKDM4E
SCHEMBL30359 0.81 AKR1B1 (0.76) BCAT2AKR1B1TDP1TSHRKDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2059546-B2 SAGGING CONTROL AGENTS COATINGS FOREIGN IP CO LLC (US) 2018-09-19 EP disclosed
EP-2059548-B1 AQUEOUS COMPOSITIONS OF SAGGING CONTROL AGENTS COATINGS FOREIGN IP CO LLC (US) 2015-07-15 EP disclosed
EP-2059546-B1 SAGGING CONTROL AGENTS COATINGS FOREIGN IP CO LLC (US) 2015-03-11 EP disclosed
EP-2059548-A2 AQUEOUS COMPOSITIONS OF SAGGING CONTROL AGENTS E.I. DU PONT DE NEMOURS AND COMPANY (US) 2009-05-20 EP disclosed
EP-2059546-A1 SAGGING CONTROL AGENTS E.I. DU PONT DE NEMOURS AND COMPANY (US) 2009-05-20 EP disclosed
EP-1671990-B1 Aqueous coating compositions DU PONT (US) 2009-03-11 EP disclosed
US-20080132638-A1 Aqueous compositions of sagging control agents E. I. DU PONT DE NEMOURS AND COMPANY 2008-06-05 US disclosed
US-20080132639-A1 Sagging control agents E. I. DU PONT DE NEMOURS AND COMPANY 2008-06-05 US disclosed
WO-2008030437-A2 AQUEOUS COMPOSITIONS OF SAGGING CONTROL AGENTS E. I. DU PONT DE NEMOURS AND COMPANY (US) 2008-03-13 WO disclosed
WO-2008030445-A1 SAGGING CONTROL AGENTS E. I. DU PONT DE NEMOURS AND COMPANY (US) 2008-03-13 WO disclosed
EP-1671990-A2 Aqueous coating compositions E.I.Du pont de nemours and company (US) 2006-06-21 EP disclosed