SCHEMBL3975690

SCHEMBL3975690

CCO[Si](CC([NH])=O)(OCC)OCC

nearest known ligand 0.34

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 3/20 0.32
LMNA P02545 1/20 0.31
HSD17B10 Q99714 1/20 0.31
TDP1 Q9NUW8 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1093452 0.77 FFAR3 (0.38) ALDH1A1LMNAHSD17B10TDP1
SCHEMBL28132688 0.77 ALDH1A1 (0.45) ALDH1A1LMNAHSD17B10TDP1
SCHEMBL9810225 0.76
SCHEMBL19194876 0.75 ALOX15 (0.40) ALDH1A1LMNAHSD17B10TDP1
SCHEMBL3920887 0.75 GAA (0.52) ALDH1A1LMNAHSD17B10
SCHEMBL8158156 0.75 CA12 (0.31)
Lithium Ion SCHEMBL3911402 0.73 FFAR3 (0.35) ALDH1A1
SCHEMBL3912265 0.73 TSHR (0.42) ALDH1A1LMNAHSD17B10
Potassium Ion SCHEMBL3915177 0.73 FFAR3 (0.35) ALDH1A1
SCHEMBL960274 0.70 CTSD (0.43) ALDH1A1LMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2057341-A1 ADHESIVE JOINT SEALED WITH SILICONE Sika Technology AG (CH) 2009-05-13 EP disclosed
WO-2008000833-A1 ADHESIVE JOINT SEALED WITH SILICONE SIKA TECHNOLOGY AG (CH) 2008-01-03 WO disclosed
EP-1873344-A1 Silicone sealed bonding Sika Technology AG (CH) 2008-01-02 EP disclosed
EP-0885933-B1 One-component alkoxy containing RTV-silicone rubber compositions WACKER CHEMIE GMBH (DE) 2000-08-30 EP disclosed
US-6020449-A Alkoxy-crosslinking RTV1 silicone rubber mixtures WACKER-CHEMIE GMBH (DE) 2000-02-01 US disclosed
US-6001948-A BASED ON HYDROXY-TERMINATED POLYDIORGANOSILOXANES CONTAINING A TRIALKOXYSILANE WITH A SUBSTITUTED AMIDOALKYL RADICAL, WHICH CAN BE PREPARED USING CONVENTIONAL MIXING TECHNOLOGIES. WACKER-CHEMIE GMBH (DE) 1999-12-14 US disclosed
EP-0885931-A2 One-component alkoxy group containing RTV-systems Hüls Silicone Gesellschaft mit beschränkter Haftung (DE) 1998-12-23 EP disclosed
EP-0885933-A1 One-component alkoxy containing RTV-silicone rubber compositions Hüls Silicone Gesellschaft mit beschränkter Haftung (DE) 1998-12-23 EP disclosed