Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL591603 | 0.89 | HTR1D (0.33) | BRD4 | |
| SCHEMBL589220 | 0.85 | RORC (0.31) | BRD4 | |
| SCHEMBL591483 | 0.85 | HTR1D (0.32) | BRD4 | |
| SCHEMBL591485 | 0.82 | NTSR1 (0.39) | — | |
| SCHEMBL592327 | 0.81 | CNR2 (0.32) | — | |
| SCHEMBL589726 | 0.80 | NTSR1 (0.35) | — | |
| SCHEMBL3977928 | 0.73 | SLC6A4 (0.35) | — | |
| SCHEMBL590969 | 0.73 | RORC (0.33) | — | |
| SCHEMBL591502 | 0.73 | BRD4 (0.35) | BRD4 | |
| SCHEMBL591036 | 0.71 | CHRNB2 (0.37) | KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2120932-A1 | INDAZOLE DERIVATIVES AS KINASE INHIBITORS FOR THE TREATMENT OF CANCER | Nerviano Medical Sciences S.r.l. (IT) | 2009-11-25 | — | — | EP | disclosed |
| WO-2008074749-A9 | INDAZOLE DERIVATIVES AS KINASE INHIBITORS FOR THE TREATMENT OF CANCER | NERVIANO MEDICAL SCIENCES SRL (IT) | 2009-05-07 | — | — | WO | disclosed |
| WO-2008074749-A1 | INDAZOLE DERIVATIVES AS KINASE INHIBITORS FOR THE TREATMENT OF CANCER | NERVIANO MEDICAL SCIENCES S.R.L. (IT) | 2008-06-26 | — | — | WO | disclosed |