Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPA1 | O75762 | 3/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL664142 | 0.86 | — | — | |
| SCHEMBL6245462 | 0.79 | TRPA1 (0.34) | TRPA1 | |
| SCHEMBL2448820 | 0.78 | LARS1 (0.33) | TRPA1 | |
| SCHEMBL25309170 | 0.77 | TRPA1 (0.32) | TRPA1 | |
| SCHEMBL1071095 | 0.77 | TRPA1 (0.32) | TRPA1 | |
| SCHEMBL1145020 | 0.75 | TRPA1 (0.40) | TRPA1 | |
| SCHEMBL3656632 | 0.75 | — | — | |
| SCHEMBL136235 | 0.74 | GABRA1 (0.35) | — | |
| SCHEMBL3408683 | 0.74 | TSHR (0.31) | — | |
| SCHEMBL14661575 | 0.72 | RIPK1 (0.31) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2054504-A2 | RETINOID COMPOUNDS AND THEIR USE | REINNERVATE LIMITED (GB) | 2009-05-06 | — | — | EP | claimed |
| WO-2008025965-A2 | RETINOID COMPOUNDS AND THEIR USE | REINNERVATE LIMITED (GB) | 2008-03-06 | — | — | WO | claimed |