SCHEMBL3976205

SCHEMBL3976205

NNC(=O)c1occc1-c1cccc(OCC(O)c2ccccc2)c1

nearest known ligand 0.47

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
LTA4H P09960 1/20 0.39
FABP4 P15090 1/20 0.38
KMT2A Q03164 3/20 0.37
MEN1 O00255 2/20 0.37
ALDH1A1 P00352 3/20 0.36
GAA P10253 3/20 0.36
KDM4E B2RXH2 2/20 0.36
MAPT P10636 2/20 0.36
LMNA P02545 1/20 0.36
HTT P42858 1/20 0.36
SMN1; SMN2 Q16637 1/20 0.36
FABP1 P07148 1/20 0.36
FAAH O00519 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3978230 0.83 PTGS2 (0.40) FABP4KMT2AMEN1ALDH1A1KDM4E
SCHEMBL3975306 0.82 SMPD1 (0.49) ALDH1A1MAPTSMN1; SMN2
SCHEMBL3978096 0.82 MEN1 (0.50) KMT2AMEN1ALDH1A1GAAKDM4E
SCHEMBL3973274 0.81 NR1H4 (0.51) ALDH1A1GAAKDM4ELMNAHTT
SCHEMBL3976171 0.80 GCGR (0.36)
SCHEMBL3977706 0.79 TDP1 (0.41) KMT2AMEN1ALDH1A1GAAMAPT
SCHEMBL3978696 0.77 PTGER4 (0.44) KMT2AMEN1KDM4EMAPTSMN1; SMN2
SCHEMBL4285451 0.76 MAPT (0.43) KMT2AMEN1ALDH1A1GAAKDM4E
SCHEMBL3977184 0.75 GPR132 (0.46) KMT2AMEN1ALDH1A1GAAMAPT
SCHEMBL3978209 0.74 CA12 (0.39) KMT2AMEN1GAAKDM4EMAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7514452-B2 2-furancarboxylic acid hydrazides and pharmaceutical compositions containing the same DAINIPPON PHARMACEUTICAL CO., LTD (JP) 2009-04-07 US disclosed
US-20050171196-A1 2-Furancarboxylic acid hydrazides and pharmaceutical compositions containing the same DAINIPPON SUMITOMO PHARMA CO., LTD. (JP) 2005-08-04 US disclosed
EP-1489077-A1 2-FURANCARBOXYLIC ACID HYDRAZIDES AND PHARMACEUTICAL COMPOSITIONS CONTAINING THE SAME DAINIPPON PHARMACEUTICAL CO., LTD. (JP) 2004-12-22 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20050171196-A1 2-Furancarboxylic acid hydrazides and pharmaceutical compositions containing the same GLP1R, GCGR, GPR119 LTA4H 1198/4885FABP4 1815/4885KMT2A 3459/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.