Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA1 | P30542 | 3/20 | 1.00 |
| ▸ | CNR2 | P34972 | 3/20 | 0.57 |
| ▸ | MAPT | P10636 | 2/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.52 |
| ▸ | MEN1 | O00255 | 1/20 | 0.52 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.52 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.52 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.52 |
| ▸ | RORB | Q92753 | 7/20 | 0.47 |
| ▸ | SRD5A2 | P31213 | 1/20 | 0.45 |
| ▸ | CNR1 | P21554 | 1/20 | 0.44 |
| ▸ | GRM6 | O15303 | 1/20 | 0.43 |
| ▸ | CES2 | O00748 | 1/20 | 0.41 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4090650 | 0.87 | ADORA1 (0.77) | ADORA1CNR2MAPTALDH1A1MEN1 | |
| SCHEMBL4080808 | 0.86 | ADORA1 (0.75) | ADORA1CNR2MAPTALDH1A1MEN1 | |
| SCHEMBL4086503 | 0.84 | ADORA1 (0.72) | ADORA1CNR2MAPTALDH1A1MEN1 | |
| SCHEMBL3976892 | 0.81 | ADORA1 (0.68) | ADORA1CNR2MAPTALDH1A1MEN1 | |
| SCHEMBL4078131 | 0.81 | ADORA1 (0.68) | ADORA1CNR2MAPTALDH1A1MEN1 | |
| SCHEMBL3974619 | 0.80 | ADORA1 (0.67) | ADORA1CNR2MAPTALDH1A1MEN1 | |
| SCHEMBL4076833 | 0.79 | ADORA1 (0.66) | ADORA1CNR2MAPTALDH1A1MEN1 | |
| SCHEMBL3976346 | 0.78 | ADORA1 (0.63) | ADORA1CNR2MAPTALDH1A1MEN1 | |
| SCHEMBL3980569 | 0.76 | ADORA1 (0.61) | ADORA1CNR2MAPTALDH1A1MEN1 | |
| SCHEMBL4091364 | 0.72 | ADORA1 (0.56) | ADORA1CNR2MAPTRORB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009049362-A1 | A1 ADENOSINE RECEPTOR ALLOSTERIC ENHANCERS | MONASH UNIVERSITY (AU) | 2009-04-23 | — | — | WO | disclosed |