SCHEMBL3976437

SCHEMBL3976437

COc1cc(C23CC4CC(C2)CC(c2cc(OC)c(O)c(OC)c2)(C4)C3)cc(OC)c1O

nearest known ligand 0.42

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
LMNA P02545 4/20 0.42
SMN1; SMN2 Q16637 2/20 0.41
MAPT P10636 2/20 0.41
KDM4E B2RXH2 1/20 0.41
NPC1 O15118 1/20 0.41
RAB9A P51151 1/20 0.41
MDM2 Q00987 1/20 0.41
KMT2A Q03164 4/20 0.40
MEN1 O00255 3/20 0.40
GAA P10253 3/20 0.40
FAAH O00519 1/20 0.40
RECQL P46063 1/20 0.40
ESR1 P03372 1/20 0.40
PGR P06401 2/20 0.39
PTPN1 P18031 1/20 0.38
PPARD Q03181 1/20 0.38
POLB P06746 1/20 0.38
GFER P55789 1/20 0.38
ALDH1A1 P00352 1/20 0.37
CA12 O43570 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11645079 0.90 KMT2A (0.47) LMNANPC1KMT2AMEN1GAA
SCHEMBL4582054 0.90 ALDH1A1 (0.39) LMNASMN1; SMN2MAPTKDM4ENPC1
SCHEMBL27199178 0.83 KMT2A (0.53) KMT2AMEN1GAAFAAHPOLB
SCHEMBL2002660 0.83 KMT2A (0.53) LMNASMN1; SMN2MAPTKDM4ENPC1
SCHEMBL3971722 0.83 ESR1 (0.43) LMNASMN1; SMN2KMT2AMEN1GAA
SCHEMBL12936012 0.81 ERN1 (0.44) LMNASMN1; SMN2MAPTKDM4ENPC1
SCHEMBL2048427 0.77 ACHE (0.43) LMNASMN1; SMN2NPC1RAB9AKMT2A
SCHEMBL3978480 0.76 PTPN1 (0.40) LMNASMN1; SMN2MAPTKDM4EKMT2A
SCHEMBL3975973 0.75 MEN1 (0.42) LMNASMN1; SMN2NPC1RAB9AKMT2A
SCHEMBL4582977 0.74 ESR1 (0.39) LMNASMN1; SMN2MAPTKDM4EKMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1469026-B1 AROMATIC POLYCARBONATE RESIN PROCESS FOR PRODUCING THE SAME OPTICAL PART MOLDING MATERIAL AND OPTICAL PART IDEMITSU KOSAN CO (JP) 2009-05-06 EP disclosed
US-7329718-B2 Aromatic polycarbonate resin, process for producing the same, optical-part molding material, and optical part IDEMITSU KOSAN CO., LTD. (JP) 2008-02-12 US disclosed
US-20060270823-A1 Suited to a molding material for an optical disc substrate such as a digital audio disc, a digital video disc and an optical memory disc, various lenses such as a lens for an optical pickup, spectacle lenses, contact lenses and a lens sheet, an optical sheet substrate IDEMITSU KOSAN CO., LTD (JP) 2006-11-30 US disclosed
US-7112644-B2 Aromatic polycarbonate resin, process for producing the same, optical-part molding material, and optical part IDEMITSU KOSAN CO., LTD. (JP) 2006-09-26 US disclosed
US-20050143553-A1 Aromatic polycarbonate resin, process for producing the same, optical-part molding material, and optical part IDEMITSU KOSAN CO., LTD (JP) 2005-06-30 US disclosed
EP-1469026-A1 AROMATIC POLYCARBONATE RESIN PROCESS FOR PRODUCING THE SAME OPTICAL PART MOLDINGMATERIAL AND OPTICAL PART IDEMITSU KOSAN CO., LTD. (JP) 2004-10-20 EP disclosed