SCHEMBL2048427

SCHEMBL2048427

Cc1cc(C23CC4CC(C2)CC(c2cc(C)c(O)c(C)c2)(C4)C3)cc(C)c1O

nearest known ligand 0.43

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ACHE P22303 1/20 0.43
MEN1 O00255 3/20 0.41
KMT2A Q03164 3/20 0.41
POLB P06746 1/20 0.41
GAA P10253 1/20 0.41
GFER P55789 1/20 0.41
ALDH1A1 P00352 2/20 0.40
ESR1 P03372 1/20 0.40
GRIN2D O15399 1/20 0.39
GRIN3B O60391 1/20 0.39
GRIN1 Q05586 1/20 0.39
GRIN2A Q12879 1/20 0.39
GRIN2B Q13224 1/20 0.39
GRIN2C Q14957 1/20 0.39
GRIN3A Q8TCU5 1/20 0.39
PGR P06401 4/20 0.37
LMNA P02545 1/20 0.37
CA1 P00915 1/20 0.37
CA2 P00918 1/20 0.37
HSD11B1 P28845 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27451016 0.89 MEN1 (0.52) ACHEMEN1KMT2APOLBGAA
SCHEMBL6762622 0.89 ACHE (0.46) ACHEMEN1KMT2APOLBGAA
SCHEMBL4585737 0.89 ALDH1A1 (0.42) ACHEMEN1KMT2APOLBGAA
SCHEMBL209155 0.86 SHBG (0.42) ACHEMEN1KMT2APOLBGAA
SCHEMBL211920 0.85 ERN1 (0.39) ACHEMEN1KMT2APOLBGAA
SCHEMBL29518698 0.81 PGR (0.44) MEN1KMT2APOLBGAAGFER
SCHEMBL4957525 0.81 MEN1 (0.37) MEN1KMT2APOLBGAAGFER
SCHEMBL4949759 0.81 ESR1 (0.32) MEN1KMT2APOLBGAAGFER
SCHEMBL17042471 0.81 ACHE (0.40) ACHEMEN1KMT2APOLBGAA
SCHEMBL29485576 0.81 MEN1 (0.57) MEN1KMT2APOLBGAAGFER

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7960483-B2 Adamantane derivative, composition comprising the derivative, and optical and electronic member using the composition IDEMITSU KOSAN CO., LTD. (JP) 2011-06-14 US disclosed
EP-1469026-B1 AROMATIC POLYCARBONATE RESIN PROCESS FOR PRODUCING THE SAME OPTICAL PART MOLDING MATERIAL AND OPTICAL PART IDEMITSU KOSAN CO (JP) 2009-05-06 EP disclosed
US-20090062481-A1 ADAMANTANE DERIVATIVE, COMPOSITION COMPRISING THE DERIVATIVE, AND OPTICAL AND ELECTRONIC MEMBER USING THE COMPOSITION IDEMITSU KOSAN CO., LTD. (JP) 2009-03-05 US disclosed
EP-1985617-A1 ADAMANTANE DERIVATIVE, COMPOSITION COMPRISING THE DERIVATIVE, AND OPTICAL AND ELECTRONIC MEMBER USING THE COMPOSITION Idemitsu Kosan Co., Ltd. (JP) 2008-10-29 EP disclosed
EP-1336597-B1 Hydroxyphenyl adamantanes and process for the production of the same HONSHU CHEMICAL IND (JP) 2008-07-16 EP disclosed
US-7329718-B2 Aromatic polycarbonate resin, process for producing the same, optical-part molding material, and optical part IDEMITSU KOSAN CO., LTD. (JP) 2008-02-12 US disclosed
US-20060270823-A1 Suited to a molding material for an optical disc substrate such as a digital audio disc, a digital video disc and an optical memory disc, various lenses such as a lens for an optical pickup, spectacle lenses, contact lenses and a lens sheet, an optical sheet substrate IDEMITSU KOSAN CO., LTD (JP) 2006-11-30 US disclosed
US-7112644-B2 Aromatic polycarbonate resin, process for producing the same, optical-part molding material, and optical part IDEMITSU KOSAN CO., LTD. (JP) 2006-09-26 US disclosed
US-20050143553-A1 Aromatic polycarbonate resin, process for producing the same, optical-part molding material, and optical part IDEMITSU KOSAN CO., LTD (JP) 2005-06-30 US disclosed
EP-1469026-A1 AROMATIC POLYCARBONATE RESIN PROCESS FOR PRODUCING THE SAME OPTICAL PART MOLDINGMATERIAL AND OPTICAL PART IDEMITSU KOSAN CO., LTD. (JP) 2004-10-20 EP disclosed
US-6720460-B2 FORMING HEAT RESISTANT, MECHANICAL STRENGTH POLYMER ADDITIVES; ACID CATALYZED REACTION OF ADAMANTANE DIOL OR TRIOL WITH PHENOLIC DERIVATIVE HONSHU CHEMICAL INDUSTRY CO., LTD. (JP) 2004-04-13 US disclosed
US-20030187307-A1 Hydroxyphenyl adamantanes and process for the production of the same HONSHU CHEMICAL INDUSTRY CO., LTD. (JP) 2003-10-02 US disclosed
EP-1336597-A1 Hydroxyphenyl adamantanes and process for the production of the same Honshu Chemical Industry Co., Ltd. (JP) 2003-08-20 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20030187307-A1 Hydroxyphenyl adamantanes and process for the production of the same CYP8B1, DHPS, P4HA1 ACHE 829/4885MEN1 1025/4885KMT2A 4019/4885
US-20090062481-A1 ADAMANTANE DERIVATIVE, COMPOSITION COMPRISING THE DERIVATIVE, AND OPTICAL AND ELECTRONIC MEMBER USING THE COMPOSITION APP, ADAM17, PSD ACHE 67/4885MEN1 2085/4885KMT2A 1948/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.