Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NAMPT | P43490 | 2/20 | 0.56 |
| ▸ | GAA | P10253 | 1/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.51 |
| ▸ | MAPKAPK2 | P49137 | 4/20 | 0.50 |
| ▸ | POLB | P06746 | 1/20 | 0.50 |
| ▸ | RAB9A | P51151 | 1/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.50 |
| ▸ | HPGD | P15428 | 1/20 | 0.50 |
| ▸ | MAPT | P10636 | 2/20 | 0.49 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.49 |
| ▸ | MEN1 | O00255 | 2/20 | 0.49 |
| ▸ | LMNA | P02545 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16193025 | 0.92 | NAMPT (0.60) | NAMPTGAAALDH1A1MAPKAPK2POLB | |
| SCHEMBL3975984 | 0.88 | NAMPT (0.57) | NAMPTGAAALDH1A1MAPKAPK2HPGD | |
| SCHEMBL3975014 | 0.88 | MAPKAPK2 (0.57) | GAAALDH1A1MAPKAPK2POLBSMN1; SMN2 | |
| SCHEMBL1258475 | 0.87 | NAMPT (0.62) | NAMPTGAAALDH1A1POLBRAB9A | |
| SCHEMBL5388847 | 0.84 | NAMPT (0.58) | NAMPTGAAMAPKAPK2MAPTTDP1 | |
| SCHEMBL19694494 | 0.82 | NAMPT (0.62) | NAMPTGAASMN1; SMN2MAPTTDP1 | |
| SCHEMBL3180689 | 0.81 | L3MBTL1 (0.61) | NAMPTGAAMAPTTDP1 | |
| SCHEMBL5386906 | 0.81 | ALDH1A1 (0.56) | NAMPTALDH1A1POLBRAB9AHPGD | |
| SCHEMBL8253777 | 0.81 | NAMPT (0.60) | NAMPTGAAALDH1A1MAPTTDP1 | |
| SCHEMBL2589540 | 0.81 | NAMPT (0.60) | NAMPTGAAALDH1A1MAPTTDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009053448-A1 | COMPOUNDS WHICH POTENTIATE AMPA RECEPTOR AND USES THEREOF IN MEDICINE | GLAXO GROUP LIMITED (GB) | 2009-04-30 | — | — | WO | disclosed |
| WO-2009053448-A1 | COMPOUNDS WHICH POTENTIATE AMPA RECEPTOR AND USES THEREOF IN MEDICINE | GLAXO GROUP LIMITED (GB) | 2009-04-30 | — | — | WO | disclosed |