SCHEMBL652269

SCHEMBL652269

Brc1c(Br)c(Br)c(C(Br)(c2ccccc2)C(Br)(Br)Br)c(Br)c1Br

nearest known ligand 0.35

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
KCNN4 O15554 4/20 0.35
TSHR P16473 2/20 0.35
ALDH1A1 P00352 2/20 0.35
TDP1 Q9NUW8 1/20 0.33
MAPK1 P28482 1/20 0.31
KIF11 P52732 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL653357 0.79 KCNN4 (0.45) KCNN4TSHRALDH1A1TDP1MAPK1
SCHEMBL4949944 0.76 KCNN4 (0.35) KCNN4TSHRALDH1A1TDP1MAPK1
SCHEMBL15064283 0.75 ALDH1A1 (0.38) KCNN4TSHRALDH1A1TDP1MAPK1
SCHEMBL4813303 0.75 KCNN4 (0.38) KCNN4TSHRALDH1A1TDP1MAPK1
SCHEMBL652272 0.74 CA1 (0.38) KCNN4TSHRALDH1A1TDP1MAPK1
SCHEMBL94425 0.74 CA1 (0.38) ALDH1A1MAPK1
SCHEMBL653490 0.74 CA1 (0.32) KCNN4TSHRALDH1A1MAPK1
SCHEMBL4952285 0.73 KCNN4 (0.33) KCNN4TSHRALDH1A1TDP1
SCHEMBL3977115 0.73 TSHR (0.42) KCNN4TSHRALDH1A1TDP1
SCHEMBL653858 0.73 TDP1 (0.30) TDP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 143 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2132158-B1 PREPARATION AND PROVISION OF HIGH ASSAY DECABROMODIPHENYLETHANE ALBEMARLE CORP (US) 2014-08-13 EP claimed
EP-2137118-B1 PREPARATION AND PROVISION OF HIGH ASSAY DECABROMODIPHENYLETHANE ALBEMARLE CORP (US) 2013-12-25 EP claimed
US-8354464-B2 Mixtures of brominated diphenylethanes, method of preparing the same and resin composition using the same CHEIL INDUSTRIES INC. (KR) 2013-01-15 US claimed
US-8334332-B2 Flame-retardant thermoplastic resin composition with excellent color tone CHEIL INDUSTRIES INC. (KR) 2012-12-18 US claimed
US-8329804-B2 Flame retardant thermoplastic resin composition CHEIL INDUSTRIES INC. (KR) 2012-12-11 US claimed
US-8217207-B2 Preparation and provision of high assay decabromodiphenylethane ALBEMARLE CORPORATION (US) 2012-07-10 US claimed
US-8193272-B2 Flame-retardant high impact vinyl aromatic resin composition having good fluidity CHEIL INDUSTRIES INC. (KR) 2012-06-05 US claimed
US-20110288225-A1 Preparation and Provision of High Assay Decabromodiphenylethane ALBEMARLE CORPORATION (US) 2011-11-24 US claimed
US-7977421-B2 Brominated diphenyl ethane mixtures and resin compositions including the same CHEIL INDUSTRIES INC. (KR) 2011-07-12 US claimed
US-20110160343-A1 Flame-Retardant Thermoplastic Resin Composition with Excellent Color Tone CHEIL INDUSTRIES INC. (KR) 2011-06-30 US claimed
US-20050222473-A1 Bromination process PARKS JOHN C 2005-10-06 US claimed
US-20050009992-A1 Carbon-carbon initiators for use in golf balls JPMORGAN CHASE BANK, N.A., AS SUCCESSOR ADMINISTRATIVE AGENT 2005-01-13 US claimed
EP-1449879-A1 FLAME−RETARDANT STYRENE RESIN COMPOSITION Dai-Ichi Kogyo Seiyaku Co., Ltd. (JP) 2004-08-25 EP claimed
US-20040092642-A1 Flame-retardant styrene resin composition DAI-ICHI KOGYO SEIYAKU CO., LTD. (JP) 2004-05-13 US claimed
US-20010047118-A1 Bromination process ALBEMARLE CORPORATION 2001-11-29 US claimed
US-6117371-A FLAME RETARDANT OF HEXABROMODIPHENYLALKANE, HEPTABROMODIPHENYLALKANE, AND OCTABROMODIPHENYLALKANE WHICH HAS A BROAD MELTING POINT RANGE; FLAMMABLE POLYMER AND FLAME RETARDANT GREAT LAKES CHEMICAL CORPORATION (US) 2000-09-12 US claimed
EP-0490378-A1 Bromination process ALBEMARLE CORPORATION (US) 1992-06-17 EP claimed
US-5055235-A Heating non-condensed ring polyaromatics in the presence of bromine and a halogenation catalyst ETHYL CORPORATION (US) 1991-10-08 US claimed
EP-0445595-A2 Bromination process ALBEMARLE CORPORATION (US) 1991-09-11 EP claimed
US-5039729-A Consisting of hexabromodiphenyl ethane, heptabromodiphenyl ethane and octabromodiphenyl ethane; flame retarders ETHYL CORPORATION (US) 1991-08-13 US claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20050222473-A1 Bromination process BBOX1, DDT, DEK KCNN4 1001/4885TSHR 1171/4885ALDH1A1 2420/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.