Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC4 | P56524 | 2/20 | 0.44 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.44 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.44 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.44 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | CTSK | P43235 | 1/20 | 0.40 |
| ▸ | MGLL | Q99685 | 5/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.38 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.38 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.38 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.38 |
| ▸ | DHFR | P00374 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13006061 | 0.98 | HDAC4 (0.45) | HDAC4HDAC2HDAC8HDAC6TP53 | |
| SCHEMBL380904 | 0.94 | TP53 (0.44) | HDAC4HDAC2HDAC8HDAC6TP53 | |
| Vinyl Chloride SCHEMBL8670745 | 0.86 | ALDH1A1 (0.38) | HDAC4HDAC2HDAC8HDAC6TP53 | |
| SCHEMBL432930 | 0.85 | ALDH1A1 (0.43) | TP53CYP3A4MGLLALDH1A1DHFR | |
| SCHEMBL15274799 | 0.82 | HDAC4 (0.38) | HDAC4HDAC2HDAC8HDAC6CTSK | |
| SCHEMBL7557454 | 0.81 | ALDH1A1 (0.52) | HDAC4HDAC2HDAC8HDAC6TP53 | |
| Acrylic Acid Methyl Ester SCHEMBL1470696 | 0.81 | ALDH1A1 (0.37) | HDAC4HDAC2HDAC8HDAC6TP53 | |
| Styrene SCHEMBL2876178 | 0.80 | MGLL (0.43) | MGLLDHFR | |
| SCHEMBL15274789 | 0.78 | HDAC4 (0.37) | HDAC4HDAC2HDAC8HDAC6CTSK | |
| Vinyl Chloride SCHEMBL9574774 | 0.78 | ALDH1A1 (0.41) | TP53CYP3A4MGLLALDH1A1DHFR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2173314-B1 | VAPORIZER SOLUTION, AND DYEING METHOD | HENKEL AG & CO KGAA (DE) | 2014-07-23 | — | — | EP | disclosed |
| EP-1711156-B1 | NACREOUS LUSTER-EFFECT DYE FOR KERATIN FIBERS | PROCTER & GAMBLE (US) | 2009-05-06 | — | — | EP | disclosed |
| EP-1670423-B1 | DYE-CONTAINING PELLETS FOR DYEING KERATIN FIBRES | WELLA AG (DE) | 2008-10-08 | — | — | EP | disclosed |
| EP-1584323-B1 | Use of N-hydroxyalkyl-O-benzylchitosans in hair treatment | WELLA AG (DE) | 2007-10-24 | — | — | EP | disclosed |
| EP-1584323-A1 | Use of N-hydroxyalkyl-O-benzylchitosans in hair treatment | Wella Aktiengesellschaft (DE) | 2005-10-12 | — | — | EP | disclosed |