Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 4/20 | 0.51 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | CASP3 | P42574 | 1/20 | 0.40 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.40 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.40 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 2/20 | 0.39 |
| ▸ | BCL2L1 | Q07817 | 1/20 | 0.39 |
| ▸ | BAD | Q92934 | 1/20 | 0.39 |
| ▸ | PTK2 | Q05397 | 1/20 | 0.38 |
| ▸ | BTK | Q06187 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.36 |
| ▸ | PDPK1 | O15530 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | KCNK2 | O95069 | 1/20 | 0.36 |
| ▸ | KCNK10 | P57789 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30392079 | 0.79 | EGFR (0.36) | NPC1TDP1BCL2L1BADPTK2 | |
| SCHEMBL24118185 | 0.77 | BCL2L1 (0.36) | NPC1KDM4ERAB9ABCL2L1BAD | |
| SCHEMBL28271036 | 0.76 | NPC1 (0.74) | NPC1TDP1KDM4ECYP1A2L3MBTL1 | |
| SCHEMBL23598751 | 0.75 | NPC1 (0.44) | NPC1TDP1KDM4ECYP1A2L3MBTL1 | |
| SCHEMBL3367025 | 0.74 | NPY5R (0.48) | NPC1TDP1KDM4ECYP1A2L3MBTL1 | |
| SCHEMBL23598612 | 0.74 | NPC1 (0.43) | NPC1TDP1KDM4ECYP1A2L3MBTL1 | |
| SCHEMBL3967701 | 0.74 | AR (0.43) | NPC1KDM4ECYP1A2RAB9ABCL2L1 | |
| SCHEMBL5231256 | 0.73 | CCR1 (0.47) | NPC1RAB9ABCL2L1BADCYP2A6 | |
| SCHEMBL18891552 | 0.72 | TDP1 (0.53) | NPC1TDP1KDM4ECYP1A2L3MBTL1 | |
| SCHEMBL4974372 | 0.72 | BCL2L1 (0.60) | TDP1KDM4EL3MBTL1BCL2L1BAD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090043064-A1 | METAL COMPLEX, POLYMER COMPOUND, AND DEVICE CONTAINING IT | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2009-02-12 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090043064-A1 | METAL COMPLEX, POLYMER COMPOUND, AND DEVICE CONTAINING IT | TIMCC, AP1M1, TXN | NPC1 4118/4885TDP1 3278/4885KDM4E 3949/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.