Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM2 | P08172 | 1/20 | 0.55 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.55 |
| ▸ | HPGD | P15428 | 1/20 | 0.54 |
| ▸ | HTR1A | P08908 | 1/20 | 0.52 |
| ▸ | VNN1 | O95497 | 1/20 | 0.52 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.51 |
| ▸ | BLM | P54132 | 1/20 | 0.51 |
| ▸ | CRBN | Q96SW2 | 1/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.50 |
| ▸ | RIPK1 | Q13546 | 2/20 | 0.50 |
| ▸ | TP53 | P04637 | 1/20 | 0.50 |
| ▸ | FASN | P49327 | 1/20 | 0.49 |
| ▸ | ACHE | P22303 | 1/20 | 0.49 |
| ▸ | USP2 | O75604 | 1/20 | 0.49 |
| ▸ | LMNA | P02545 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1971597 | 0.86 | CHRM2 (0.54) | CHRM2CHRM3HPGDHTR1ASIGMAR1 | |
| SCHEMBL17151131 | 0.80 | HPGD (0.58) | CHRM2CHRM3HPGDSIGMAR1BLM | |
| SCHEMBL5654896 | 0.79 | ALDH1A1 (0.57) | CHRM2CHRM3HPGDHTR1ASIGMAR1 | |
| SCHEMBL6981118 | 0.78 | HPGD (0.61) | HPGDHTR1A | |
| SCHEMBL14377678 | 0.77 | CRBN (0.49) | CHRM2CHRM3HPGDHTR1ASIGMAR1 | |
| SCHEMBL3976096 | 0.77 | MGLL (0.47) | CHRM2CHRM3HPGDHTR1ABLM | |
| SCHEMBL7129676 | 0.76 | HPGD (0.79) | HPGDSIGMAR1BLMALDH1A1ACHE | |
| SCHEMBL252026 | 0.76 | HPGD (0.79) | HPGDSIGMAR1BLMALDH1A1ACHE | |
| SCHEMBL9928309 | 0.76 | HPGD (0.61) | CHRM2CHRM3HPGDSIGMAR1BLM | |
| SCHEMBL31435878 | 0.76 | HPGD (0.61) | CHRM2CHRM3HPGDSIGMAR1BLM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009060030-A1 | HETEROARYL-SUBSTITUTED 2-PYRIDINYLMETHYLAMINE DERIVATIVES | Friedrich-Alexander-Universität Erlangen-Nürnberg (DE) | 2009-05-14 | — | — | WO | disclosed |
| EP-2058306-A1 | Heteroaryl-substituted 2-pyridinyl-methylamine derivatives | SCHWARZ PHARMA AG (DE) | 2009-05-13 | — | — | EP | disclosed |
| US-7208603-B2 | Reducing amination with cyanohydrin | PIERRE FABRE MEDICAMENT (FR) | 2007-04-24 | — | — | US | disclosed |
| EP-1358179-B1 | SYNTHESIS METHOD AND INTERMEDIATES OF PYRIDIN-2-YL-METHYLAMINE | PF MEDICAMENT (FR) | 2006-05-10 | — | — | EP | disclosed |
| US-20040116705-A1 | Reducing amination with cyanohydrin | PIERRE FABRE MEDICAMENT (FR) | 2004-06-17 | — | — | US | disclosed |
| EP-1358179-A1 | SYNTHESIS METHOD AND INTERMEDIATES OF PYRIDIN-2-YL-METHYLAMINE | PIERRE FABRE MEDICAMENT (FR) | 2003-11-05 | — | — | EP | disclosed |
| WO-2002064585-A1 | SYNTHESIS METHOD AND INTERMEDIATES OF PYRIDIN-2-YL-METHYLAMINE | PIERRE FABRE MEDICAMENT (FR) | 2002-08-22 | — | — | WO | disclosed |