Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.57 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.57 |
| ▸ | TSHR | P16473 | 1/20 | 0.57 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.57 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.47 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.47 |
| ▸ | CRBN | Q96SW2 | 1/20 | 0.47 |
| ▸ | RIPK1 | Q13546 | 2/20 | 0.46 |
| ▸ | CCR5 | P51681 | 1/20 | 0.46 |
| ▸ | HTR1A | P08908 | 1/20 | 0.46 |
| ▸ | HPGD | P15428 | 1/20 | 0.45 |
| ▸ | USP7 | Q93009 | 1/20 | 0.43 |
| ▸ | BLM | P54132 | 1/20 | 0.43 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | TP53 | P04637 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6983350 | 0.85 | HTR1A (0.55) | HTR1AHPGDPOLB | |
| SCHEMBL6984019 | 0.83 | HTR1A (0.59) | HTR1A | |
| SCHEMBL27972639 | 0.83 | CA12 (0.43) | ALDH1A1ALOX15TSHRHSD17B10HPGD | |
| SCHEMBL14525211 | 0.82 | PLA2G7 (0.45) | ALDH1A1ALOX15TSHRHSD17B10HTR1A | |
| SCHEMBL3977611 | 0.79 | CHRM2 (0.55) | ALDH1A1CHRM2CHRM3CRBNRIPK1 | |
| SCHEMBL6985229 | 0.78 | NPC1 (0.55) | POLB | |
| SCHEMBL2881785 | 0.78 | USP1 (0.56) | ALOX15TSHRCHRM2CHRM3 | |
| SCHEMBL1971597 | 0.77 | CHRM2 (0.54) | ALDH1A1CHRM2CHRM3CRBNRIPK1 | |
| SCHEMBL25336731 | 0.77 | LMNA (0.45) | ALDH1A1HSD17B10HPGDLMNA | |
| SCHEMBL30554691 | 0.77 | LMNA (0.45) | ALDH1A1HSD17B10HPGDLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7208603-B2 | Reducing amination with cyanohydrin | PIERRE FABRE MEDICAMENT (FR) | 2007-04-24 | — | — | US | disclosed |
| US-20040116705-A1 | Reducing amination with cyanohydrin | PIERRE FABRE MEDICAMENT (FR) | 2004-06-17 | — | — | US | disclosed |