Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A2 | P23975 | 15/20 | 0.53 |
| ▸ | SLC6A4 | P31645 | 14/20 | 0.53 |
| ▸ | SLC6A3 | Q01959 | 6/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5428676 | 0.76 | SLC6A2 (0.70) | SLC6A2SLC6A4SLC6A3 | |
| SCHEMBL2877349 | 0.76 | SLC6A2 (0.73) | SLC6A2SLC6A4SLC6A3 | |
| SCHEMBL8065724 | 0.75 | LMNA (0.44) | — | |
| SCHEMBL4933808 | 0.75 | AOX1 (0.42) | — | |
| Hydrochloric Acid SCHEMBL5234528 | 0.75 | SLC6A2 (0.68) | SLC6A2SLC6A4SLC6A3 | |
| SCHEMBL16097011 | 0.75 | SLC6A2 (0.64) | SLC6A2SLC6A4SLC6A3KMT2AMEN1 | |
| SCHEMBL26387507 | 0.74 | SLC6A2 (0.62) | SLC6A2SLC6A4SLC6A3KMT2AMEN1 | |
| SCHEMBL3305274 | 0.74 | PPARD (0.38) | — | |
| Hydrochloric Acid SCHEMBL5235119 | 0.72 | SLC6A2 (0.61) | SLC6A2SLC6A4SLC6A3 | |
| SCHEMBL4489240 | 0.72 | SLC6A2 (0.73) | SLC6A2SLC6A4SLC6A3KMT2AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009056693-A1 | NOVEL DERIVATIVES OF N, N'- 2, 4-DIANILINOPYRIMIDINES, PREPARATION THEREOF AS MEDICAMENTS PHARMACEUTICAL COMPOSITIONS AND IN PARTICULAR AS IKK INHIBITORS | SANOFI-AVENTIS (FR) | 2009-05-07 | — | — | WO | disclosed |