Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | AOX1 | Q06278 | 1/20 | 0.42 |
| ▸ | ACHE | P22303 | 1/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4933808 | 0.97 | AOX1 (0.42) | LMNAAOX1ACHENPSR1 | |
| SCHEMBL29774222 | 0.94 | BCHE (0.44) | LMNAACHENPSR1 | |
| SCHEMBL10126572 | 0.86 | USP2 (0.46) | LMNA | |
| SCHEMBL8995950 | 0.79 | MEN1 (0.39) | — | |
| SCHEMBL9417718 | 0.79 | TSHR (0.45) | LMNAACHE | |
| SCHEMBL8658558 | 0.78 | CETP (0.45) | — | |
| SCHEMBL5248630 | 0.78 | CETP (0.47) | AOX1ACHENPSR1 | |
| SCHEMBL16376908 | 0.77 | BCHE (0.42) | LMNAACHENPSR1 | |
| SCHEMBL31609290 | 0.77 | NPSR1 (0.43) | AOX1ACHENPSR1 | |
| SCHEMBL7331812 | 0.77 | CETP (0.47) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6054115-A | PURIFYING BY EXPOSING A MIXTURE OF UNCOORDINATED HYDROXYALKYL PHOSPHINE GROUPS AND COORDINATED HYDROXYALKYL PHOSPHINE GROUPS TO AN AMINE TO SEPARATE THE UNBOUND COORDINATED GROUPS FROM THE BOUND UNCOORDINATED GROUPS | THE CURATORS OF THE UNIVERSITY OF MISSOURI (US) | 2000-04-25 | — | — | US | disclosed |