Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.43 |
| ▸ | TSHR | P16473 | 2/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | ELANE | P08246 | 1/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.38 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.38 |
| ▸ | ATM | Q13315 | 1/20 | 0.38 |
| ▸ | STK17B | O94768 | 1/20 | 0.36 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.36 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.36 |
| ▸ | PPARD | Q03181 | 1/20 | 0.36 |
| ▸ | THRB | P10828 | 1/20 | 0.35 |
| ▸ | ESR1 | P03372 | 1/20 | 0.35 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.35 |
| ▸ | CREBBP | Q92793 | 1/20 | 0.35 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27324820 | 0.91 | TSHR (0.42) | KDM4ETSHRKMT2AMEN1ALDH1A1 | |
| SCHEMBL13385763 | 0.89 | KDM4E (0.46) | KDM4ETSHRKMT2AMEN1ALDH1A1 | |
| SCHEMBL8409499 | 0.86 | TSHR (0.39) | KDM4ETSHRKMT2AMEN1ALDH1A1 | |
| SCHEMBL14874608 | 0.85 | ELANE (0.40) | KDM4ETSHRKMT2AMEN1ALDH1A1 | |
| SCHEMBL10870368 | 0.84 | KDM4E (0.49) | KDM4ETSHRKMT2AMEN1ELANE | |
| SCHEMBL27434188 | 0.84 | KDM4E (0.49) | KDM4ETSHRKMT2AALDH1A1ELANE | |
| SCHEMBL28552774 | 0.84 | KDM4E (0.42) | KDM4ETSHRKMT2AMEN1ALDH1A1 | |
| SCHEMBL27969172 | 0.82 | THRB (0.56) | KDM4ETSHRKMT2AMEN1ALDH1A1 | |
| SCHEMBL15495926 | 0.82 | ALDH1A1 (0.48) | KDM4ETSHRKMT2AMEN1ALDH1A1 | |
| SCHEMBL27969027 | 0.82 | KDM4E (0.47) | KDM4ETSHRKMT2AMEN1ELANE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 29 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2056757-A2 | BIOCOMPATIBLE STENT | Den-Mat Holdings LLC (US) | 2009-05-13 | — | — | EP | claimed |
| WO-2008027210-A2 | BIOCOMPATIBLE STENT | DEN-MAT HOLDINGS LLC (US) | 2008-03-06 | — | — | WO | claimed |
| US-20080057096-A1 | Comprising stent body, first layer applied over stent body comprising a therapeutic substance and second layer applied over first layer comprising a fluoride-containing hydrophilic water insoluble crosslinked resin; biocompatible layer leaches fluoride to provide further therapy to patient | DEN-MAT CORPORATION | 2008-03-06 | — | — | US | claimed |
| EP-0836636-A4 | NOVEL DENTAL ADHESIVE | DEN MAT CORP (US) | 1998-10-14 | — | — | EP | claimed |
| EP-0836636-A1 | NOVEL DENTAL ADHESIVE | DEN-MAT CORPORATION (US) | 1998-04-22 | — | — | EP | claimed |
| WO-1997040770-A1 | NOVEL DENTAL ADHESIVE | DEN-MAT CORPORATION (US) | 1997-11-06 | — | — | WO | claimed |
| US-5683249-A | Dental implant process and treated prosthetic | DEN-MAT CORPORATION (US) | 1997-11-04 | — | — | US | claimed |
| WO-1997002328-A1 | NOVEL DENTAL ADHESIVE | DEN-MAT CORPORATION (US) | 1997-01-23 | — | — | WO | claimed |
| CN-104662012-B | The preparation method of the keeping method of episulfide compound and the thio epoxiess optical material using above-mentioned episulfide compound | 可奥熙搜路司有限公司 | 2017-04-05 | — | — | CN | disclosed |
| CN-104662012-A | Method for storing episulfide compound and method for preparing thioepoxy-based optical material using said episulfide compound | KOC SOLUTION CO LTD | 2015-05-27 | — | — | CN | disclosed |
| CN-104640900-A | Preparation method of thiourethane optical material | KOC SOLUTION CO LTD | 2015-05-20 | — | — | CN | disclosed |
| CN-104053657-A | Process for producing thioepoxy optical material and polymerizable composition thereof | KOC SOLUTION CO LTD | 2014-09-17 | — | — | CN | disclosed |
| CN-104039860-A | Polymerizable composition for thioepoxy-based optical material and method for producing thioepoxy-based optical material | KOC SOLUTION CO LTD | 2014-09-10 | — | — | CN | disclosed |
| CN-104024300-A | POLYMERIZABLE COMPOSITION FOR OPTICAL MATERIAL CONTAINING THIOEPOXY COMPOUND, AND PREPARATION METHOD OF OPTICAL MATERIAL | KOC SOLUTION CO LTD | 2014-09-03 | — | — | CN | disclosed |
| EP-0715636-A1 | ALLYL-EPOXY IPN | AKZO NOBEL NV (NL) | 1996-06-12 | — | — | EP | disclosed |
| WO-1996007683-A1 | ALLYL-CONTAINING EPOXY RESIN COMPOSITION COMPRISING A COPOLYMER OF AN ETHYLENICALLY UNSATURATED ANHYDRIDE AND A VINYL COMPOUND | AKZO NOBEL N.V. (NL) | 1996-03-14 | — | — | WO | disclosed |
| WO-1995006075-A1 | ALLYL-EPOXY IPN | AKZO NOBEL N.V. (NL) | 1995-03-02 | — | — | WO | disclosed |
| EP-0035574-B1 | PHOTO-POLYMERIZABLE LIGHT-SENSITIVE RESIN COMPOSITION AND LIGHT-SENSITIVE SHEET MATERIAL | ARAI, Tokuji (JP) | 1985-02-06 | — | — | EP | disclosed |
| US-4370403-A | BENZIL AND /DIMETHYLAMINO/BENZALDEHYDE PHOTOINITIATORS | Arai, Tokuji (JP) | 1983-01-25 | — | — | US | disclosed |
| EP-0035574-A1 | PHOTO-POLYMERIZABLE LIGHT-SENSITIVE RESIN COMPOSITION AND LIGHT-SENSITIVE SHEET MATERIAL | ARAI, Tokuji (JP) | 1981-09-16 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080057096-A1 | Comprising stent body, first layer applied over stent body comprising a therapeutic substance and second layer applied over first layer comprising a fluoride-containing hydrophilic water insoluble crosslinked resin; biocompatible layer leaches fluoride to provide further therapy to patient | FGB, CSTB, FGFR2 | KDM4E 4380/4885TSHR 1654/4885KMT2A 2473/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.