Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NQO2 | P16083 | 1/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | PIM1 | P11309 | 1/20 | 0.39 |
| ▸ | CSNK1A1 | P48729 | 1/20 | 0.39 |
| ▸ | CDK5 | Q00535 | 1/20 | 0.39 |
| ▸ | ROCK1 | Q13464 | 1/20 | 0.39 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.39 |
| ▸ | LRRK2 | Q5S007 | 1/20 | 0.39 |
| ▸ | CLK4 | Q9HAZ1 | 1/20 | 0.39 |
| ▸ | DYRK1B | Q9Y463 | 1/20 | 0.39 |
| ▸ | TUBB4A | P04350 | 2/20 | 0.38 |
| ▸ | TUBB | P07437 | 2/20 | 0.38 |
| ▸ | TUBA3C | P0DPH7 | 2/20 | 0.38 |
| ▸ | TUBA1B | P68363 | 2/20 | 0.38 |
| ▸ | TUBA4A | P68366 | 2/20 | 0.38 |
| ▸ | TUBB4B | P68371 | 2/20 | 0.38 |
| ▸ | TUBB3 | Q13509 | 2/20 | 0.38 |
| ▸ | TUBB2A | Q13885 | 2/20 | 0.38 |
| ▸ | TUBB8 | Q3ZCM7 | 2/20 | 0.38 |
| ▸ | TUBA3E | Q6PEY2 | 2/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27085892 | 0.78 | PIM1 (0.41) | NQO2KDM4EPIM1CSNK1A1CDK5 | |
| SCHEMBL3044760 | 0.75 | NQO2 (0.50) | NQO2KDM4EPLK4AURKAFLT4 | |
| SCHEMBL28936137 | 0.74 | CDK5 (0.53) | NQO2KDM4EPIM1CSNK1A1CDK5 | |
| SCHEMBL29920017 | 0.74 | CDK5 (0.53) | NQO2KDM4EPIM1CSNK1A1CDK5 | |
| SCHEMBL28651773 | 0.72 | HTR2A (0.49) | KDM4EPIM1CSNK1A1CDK5ROCK1 | |
| SCHEMBL30775216 | 0.72 | ALDH1A1 (0.47) | NQO2KDM4ECSNK1A1TUBB4ATUBB | |
| SCHEMBL1335593 | 0.72 | LRRK2 (0.50) | NQO2KDM4EPIM1CSNK1A1CDK5 | |
| SCHEMBL3972529 | 0.72 | MEN1 (0.45) | TUBB4ATUBBTUBA3CTUBA1BTUBA4A | |
| SCHEMBL14844702 | 0.70 | NCOA1 (0.41) | NQO2KDM4ETUBB4ATUBBTUBA3C | |
| SCHEMBL10200127 | 0.69 | CYP3A4 (0.49) | NQO2KDM4EPIM1ROCK1CLK4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009051417-A2 | PHENANTHRENE LACTAM DERIVATIVES HAVING ANTICANCER ACTIVITY AND METHOD FOR THE PREPARATION THEREOF | KOREA RESEARCH INSTITUTE OF CHEMICAL TECHNOLOGY (KR) | 2009-04-23 | — | — | WO | disclosed |