Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | LY96 | Q9Y6Y9 | 1/20 | 0.39 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.38 |
| ▸ | CA1 | P00915 | 2/20 | 0.37 |
| ▸ | CA2 | P00918 | 2/20 | 0.37 |
| ▸ | CA4 | P22748 | 2/20 | 0.37 |
| ▸ | CA6 | P23280 | 2/20 | 0.37 |
| ▸ | TUBB4A | P04350 | 1/20 | 0.37 |
| ▸ | TUBB | P07437 | 1/20 | 0.37 |
| ▸ | TUBA3C | P0DPH7 | 1/20 | 0.37 |
| ▸ | TUBA1B | P68363 | 1/20 | 0.37 |
| ▸ | TUBA4A | P68366 | 1/20 | 0.37 |
| ▸ | TUBB4B | P68371 | 1/20 | 0.37 |
| ▸ | TUBB3 | Q13509 | 1/20 | 0.37 |
| ▸ | TUBB2A | Q13885 | 1/20 | 0.37 |
| ▸ | TUBB8 | Q3ZCM7 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4260662 | 0.81 | PTPN1 (0.35) | MEN1KMT2ALY96PTPN1CA1 | |
| SCHEMBL3972272 | 0.81 | CA1 (0.38) | PTPN1CA1CA2CA4CA6 | |
| SCHEMBL3973494 | 0.80 | IDH1 (0.39) | MEN1KMT2APOLBTDP1LY96 | |
| SCHEMBL3979067 | 0.79 | PTPN1 (0.34) | LY96PTPN1CA1CA2CA4 | |
| SCHEMBL3973824 | 0.78 | HTR2A (0.36) | TDP1LY96CA1CA2CA4 | |
| SCHEMBL3973213 | 0.77 | HTR2A (0.42) | MEN1KMT2ALMNAPOLB | |
| SCHEMBL3977765 | 0.76 | NPC1 (0.53) | LMNAPOLBTDP1TUBB4ATUBB | |
| SCHEMBL3973392 | 0.76 | CA1 (0.35) | PTPN1CA1CA2CA4CA6 | |
| SCHEMBL3974894 | 0.76 | HTR2A (0.44) | MEN1KMT2ALMNAPOLB | |
| SCHEMBL3971360 | 0.76 | ALDH1A1 (0.43) | MEN1KMT2ALY96EGFR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009051417-A2 | PHENANTHRENE LACTAM DERIVATIVES HAVING ANTICANCER ACTIVITY AND METHOD FOR THE PREPARATION THEREOF | KOREA RESEARCH INSTITUTE OF CHEMICAL TECHNOLOGY (KR) | 2009-04-23 | — | — | WO | disclosed |