Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 1/20 | 0.46 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.39 |
| ▸ | HTR2C | P28335 | 1/20 | 0.38 |
| ▸ | DRD2 | P14416 | 2/20 | 0.37 |
| ▸ | DRD1 | P21728 | 2/20 | 0.37 |
| ▸ | DRD4 | P21917 | 1/20 | 0.37 |
| ▸ | DRD5 | P21918 | 1/20 | 0.37 |
| ▸ | DRD3 | P35462 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | MAOA | P21397 | 2/20 | 0.36 |
| ▸ | MAOB | P27338 | 2/20 | 0.36 |
| ▸ | AHR | P35869 | 1/20 | 0.36 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28358022 | 0.97 | CYP1A2 (0.43) | CYP1A2ALOX15HSD17B10CYP2A6HTR2C | |
| SCHEMBL10740554 | 0.90 | CYP2A6 (0.48) | CYP1A2ALOX15HSD17B10CYP2A6HTR2C | |
| SCHEMBL8666004 | 0.81 | CYP1A2 (0.56) | CYP1A2ALOX15HSD17B10CYP2A6HTR2C | |
| SCHEMBL29507678 | 0.74 | TSHR (0.44) | CYP1A2CYP2A6HTR2CTSHRMAOA | |
| SCHEMBL44447 | 0.74 | TSHR (0.44) | CYP1A2CYP2A6HTR2CTSHRMAOA | |
| SCHEMBL29881712 | 0.73 | — | — | |
| SCHEMBL109650 | 0.73 | CYP1A2 (0.62) | CYP1A2ALOX15HSD17B10CYP2A6HTR2C | |
| SCHEMBL22081972 | 0.73 | CYP1A2 (0.62) | CYP1A2ALOX15HSD17B10CYP2A6HTR2C | |
| SCHEMBL1525601 | 0.73 | — | — | |
| SCHEMBL8664022 | 0.71 | TSHR (0.58) | CYP1A2ALOX15HSD17B10CYP2A6HTR2C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 26 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6936634-B2 | Ruthenium (II) compounds for use in the therapy of cancer | THE UNIVERSITY COURT, THE UNIVERSITY OF EDINBURGH (UK) (GB) | 2005-08-30 | — | — | US | claimed |
| EP-1294732-B1 | RUTHENIUM (II) COMPOUNDS FOR USE IN THE THERAPY OF CANCER | UNIV EDINBURGH (GB) | 2004-08-18 | — | — | EP | claimed |
| US-20040029852-A1 | Ruthenium (ii) compounds for use in the therepy of cancer | UNIVERSITY COURT, THE UNIVERSITY OF EDINBURGH, THE (GB) | 2004-02-12 | — | — | US | claimed |
| EP-1294732-A1 | RUTHENIUM (II) COMPOUNDS FOR USE IN THE THERAPY OF CANCER | THE UNIVERSITY COURT OF THE UNIVERSITY OF EDINBURGH (GB) | 2003-03-26 | — | — | EP | claimed |
| WO-2002002572-A1 | RUTHENIUM (II) COMPOUNDS FOR USE IN THE THERAPY OF CANCER | THE UNIVERSITY COURT, THE UNIVERSITY OF EDINBURGH (GB) | 2002-01-10 | — | — | WO | claimed |
| JP-8059540-A | — | — | None | — | — | JP | disclosed |
| CN-107207628-B | Method for producing xylan-containing material | 日本制纸株式会社 | 2020-02-21 | — | — | CN | disclosed |
| CN-107207628-A | Method for producing xylan-containing material | 日本制纸株式会社 | 2017-09-26 | — | — | CN | disclosed |
| US-20090318402-A1 | RUTHENIUM (II) COMPOUNDS | THE UNIVERSITY COURT OF THE UNIVERSITY OF EDINBURG (GB) | 2009-12-24 | — | — | US | disclosed |
| US-20090186864-A1 | RUTHENIUM (II) COMPOUNDS | THE UNIVERSITY COURT OF THE UNIVERSITY OF EDINBURGH (GB) | 2009-07-23 | — | — | US | disclosed |
| EP-2056801-A1 | RUTHENIUM II COMPOUNDS | The University Court of the University of Edinburgh (GB) | 2009-05-13 | — | — | EP | disclosed |
| EP-1558620-B1 | RUTHENIUM ANTICANCER COMPLEXES | UNIV EDINBURGH (GB) | 2008-09-10 | — | — | EP | disclosed |
| US-6936634-B2 | Ruthenium (II) compounds for use in the therapy of cancer | THE UNIVERSITY COURT, THE UNIVERSITY OF EDINBURGH (UK) (GB) | 2005-08-30 | — | — | US | disclosed |
| EP-1558620-A1 | RUTHENIUM ANTICANCER COMPLEXES | THE UNIVERSITY COURT OF THE UNIVERSITY OF EDINBURGH (GB) | 2005-08-03 | — | — | EP | disclosed |
| EP-1294732-B1 | RUTHENIUM (II) COMPOUNDS FOR USE IN THE THERAPY OF CANCER | UNIV EDINBURGH (GB) | 2004-08-18 | — | — | EP | disclosed |
| US-20040029852-A1 | Ruthenium (ii) compounds for use in the therepy of cancer | UNIVERSITY COURT, THE UNIVERSITY OF EDINBURGH, THE (GB) | 2004-02-12 | — | — | US | disclosed |
| WO-2004005304-A1 | RUTHENIUM ANTICANCER COMPLEXES | THE UNIVERSITY COURT, THE UNIVERSITY OF EDINBURGH (GB) | 2004-01-15 | — | — | WO | disclosed |
| EP-1294732-A1 | RUTHENIUM (II) COMPOUNDS FOR USE IN THE THERAPY OF CANCER | THE UNIVERSITY COURT OF THE UNIVERSITY OF EDINBURGH (GB) | 2003-03-26 | — | — | EP | disclosed |
| WO-2002002572-A1 | RUTHENIUM (II) COMPOUNDS FOR USE IN THE THERAPY OF CANCER | THE UNIVERSITY COURT, THE UNIVERSITY OF EDINBURGH (GB) | 2002-01-10 | — | — | WO | disclosed |
| JP-H0859540-A | PRODUCTION OF FINE PARTICULATE ANTHRAQUINONE AND METHOD FOR FEEDING | KAWASAKI KASEI CHEM LTD | 1996-03-05 | — | — | JP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090186864-A1 | RUTHENIUM (II) COMPOUNDS | CBR3, RRS1, CBR1 | CYP1A2 368/4885ALOX15 846/4885HSD17B10 522/4885 |
| US-20090318402-A1 | RUTHENIUM (II) COMPOUNDS | NR0B1, NR0B2, NR2E1 | CYP1A2 918/4885ALOX15 4466/4885HSD17B10 2149/4885 |
| US-20040029852-A1 | Ruthenium (ii) compounds for use in the therepy of cancer | BRCA1, NFE2L2, RBBP7 | CYP1A2 302/4885ALOX15 704/4885HSD17B10 1020/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.