Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.47 |
| ▸ | TSHR | P16473 | 2/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.44 |
| ▸ | PDE2A | O00408 | 1/20 | 0.41 |
| ▸ | PDE5A | O76074 | 1/20 | 0.41 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.41 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.41 |
| ▸ | APEX1 | P27695 | 1/20 | 0.41 |
| ▸ | PDE4A | P27815 | 1/20 | 0.41 |
| ▸ | BLM | P54132 | 1/20 | 0.41 |
| ▸ | PDE1B | Q01064 | 1/20 | 0.41 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.41 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.41 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.41 |
| ▸ | PDE7A | Q13946 | 1/20 | 0.41 |
| ▸ | PDE1C | Q14123 | 1/20 | 0.41 |
| ▸ | PDE7B | Q9NP56 | 1/20 | 0.41 |
| ▸ | PTPRC | P08575 | 1/20 | 0.39 |
| ▸ | S100A4 | P26447 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13669497 | 0.76 | MAPT (0.51) | ALDH1A1TSHRTDP1CYP3A4PTPRC | |
| SCHEMBL5611161 | 0.75 | NOTUM (0.44) | ALDH1A1MAPTLMNAL3MBTL1MEN1 | |
| SCHEMBL9003739 | 0.74 | SMN1; SMN2 (0.54) | ALDH1A1TSHRTDP1MAPTLMNA | |
| SCHEMBL13844162 | 0.74 | SMN1; SMN2 (0.35) | ALDH1A1TSHRSMN1; SMN2 | |
| SCHEMBL27182260 | 0.72 | CYP19A1 (0.50) | ALDH1A1TSHRCYP3A4MAPTLMNA | |
| SCHEMBL4543383 | 0.70 | ALDH1A1 (0.47) | ALDH1A1TDP1PTPRCS100A4MAPT | |
| SCHEMBL1842317 | 0.70 | SMN1; SMN2 (0.48) | ALDH1A1TSHRSMN1; SMN2CASP3 | |
| SCHEMBL5635021 | 0.68 | SMN1; SMN2 (0.43) | ALDH1A1TSHRSMN1; SMN2CASP3 | |
| SCHEMBL7471914 | 0.68 | TDP1 (0.55) | ALDH1A1TSHRTDP1CYP3A4PTPRC | |
| SCHEMBL429611 | 0.68 | ALDH1A1 (0.55) | ALDH1A1TSHRTDP1CYP3A4PDE2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009058919-A1 | CCR5 ANTAGONISTS AS THERAPEUTIC AGENTS | SMITHKLINE BEECHAM CORPORATION (US) | 2009-05-07 | — | — | WO | disclosed |