Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.44 |
| ▸ | GAA | P10253 | 2/20 | 0.41 |
| ▸ | MGAM | O43451 | 1/20 | 0.41 |
| ▸ | SI | P14410 | 1/20 | 0.41 |
| ▸ | MGAM2 | Q2M2H8 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 7/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.41 |
| ▸ | NPC1 | O15118 | 3/20 | 0.41 |
| ▸ | RAB9A | P51151 | 3/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.41 |
| ▸ | APAF1 | O14727 | 1/20 | 0.41 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.41 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.41 |
| ▸ | F2 | P00734 | 1/20 | 0.40 |
| ▸ | C1R | P00736 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7967638 | 0.91 | ALDH1A1 (0.45) | ALDH1A1TDP1L3MBTL1GAAMGAM | |
| SCHEMBL8563304 | 0.80 | HTT (0.39) | ALDH1A1GAAMAPTKMT2ARAB9A | |
| SCHEMBL11065091 | 0.79 | HTR6 (0.37) | ALDH1A1TDP1MAPTKMT2ANPC1 | |
| SCHEMBL218213 | 0.78 | SMN1; SMN2 (0.50) | SMN1; SMN2ADRA2AADRA2BADRA2C | |
| SCHEMBL29420719 | 0.78 | SMN1; SMN2 (0.50) | SMN1; SMN2ADRA2AADRA2BADRA2C | |
| SCHEMBL8564839 | 0.77 | CYP1A2 (0.37) | ALDH1A1TDP1L3MBTL1MAPTKMT2A | |
| SCHEMBL8922899 | 0.77 | CYP1A2 (0.46) | ALDH1A1TDP1L3MBTL1GAAMAPT | |
| SCHEMBL10605992 | 0.77 | ALDH1A1 (0.42) | ALDH1A1L3MBTL1MAPTKMT2ASMN1; SMN2 | |
| SCHEMBL381604 | 0.77 | SMN1; SMN2 (0.49) | SMN1; SMN2ADRA2AADRA2BADRA2C | |
| SCHEMBL8567837 | 0.73 | KMT2A (0.40) | ALDH1A1TDP1L3MBTL1MAPTKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 26 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4185571-B1 | SYNTHESIS OF HETEROCYCLIC COMPOUNDS FROM CARBOXAMIDE AND CARBOXAMIDE DERIVATIVES WITH HALOALKANOLS | UNIV OF KWAZULU NATAL (ZA) | 2026-05-20 | — | — | EP | claimed |
| US-12441721-B2 | Synthesis of heterocyclic compounds from carboxamide and carboxamide derivatives with haloalkanols | UNIVERSITY OF KWAZULU-NATAL (ZA) | 2025-10-14 | — | — | US | claimed |
| US-20230295139-A1 | SYNTHESIS OF HETEROCYCLIC COMPOUNDS FROM CARBOXAMIDE AND CARBOXAMIDE DERIVATIVES WITH HALOALKANOLS | UNIVERSITY OF KWAZULU-NATAL (ZA) | 2023-09-21 | — | — | US | claimed |
| EP-4185571-A2 | SYNTHESIS OF HETEROCYCLIC COMPOUNDS FROM CARBOXAMIDE AND CARBOXAMIDE DERIVATIVES WITH HALOALKANOLS | University Of Kwazulu-Natal (ZA) | 2023-05-31 | — | — | EP | claimed |
| EP-4185571-B1 | SYNTHESIS OF HETEROCYCLIC COMPOUNDS FROM CARBOXAMIDE AND CARBOXAMIDE DERIVATIVES WITH HALOALKANOLS | UNIV OF KWAZULU NATAL (ZA) | 2026-05-20 | — | — | EP | disclosed |
| US-12441721-B2 | Synthesis of heterocyclic compounds from carboxamide and carboxamide derivatives with haloalkanols | UNIVERSITY OF KWAZULU-NATAL (ZA) | 2025-10-14 | — | — | US | disclosed |
| EP-4556468-A2 | SYNTHESIS OF HETEROCYCLIC COMPOUNDS FROM CARBOXAMIDE AND CARBOXAMIDE DERIVATIVES WITH HALOALKANOLS | University of KwaZulu-Natal (ZA) | 2025-05-21 | — | — | EP | disclosed |
| US-20230295139-A1 | SYNTHESIS OF HETEROCYCLIC COMPOUNDS FROM CARBOXAMIDE AND CARBOXAMIDE DERIVATIVES WITH HALOALKANOLS | UNIVERSITY OF KWAZULU-NATAL (ZA) | 2023-09-21 | — | — | US | disclosed |
| US-20230295139-A1 | SYNTHESIS OF HETEROCYCLIC COMPOUNDS FROM CARBOXAMIDE AND CARBOXAMIDE DERIVATIVES WITH HALOALKANOLS | UNIVERSITY OF KWAZULU-NATAL (ZA) | 2023-09-21 | — | — | US | disclosed |
| US-20230295139-A1 | SYNTHESIS OF HETEROCYCLIC COMPOUNDS FROM CARBOXAMIDE AND CARBOXAMIDE DERIVATIVES WITH HALOALKANOLS | UNIVERSITY OF KWAZULU-NATAL (ZA) | 2023-09-21 | — | — | US | disclosed |
| EP-4185571-A2 | SYNTHESIS OF HETEROCYCLIC COMPOUNDS FROM CARBOXAMIDE AND CARBOXAMIDE DERIVATIVES WITH HALOALKANOLS | University Of Kwazulu-Natal (ZA) | 2023-05-31 | — | — | EP | disclosed |
| CN-101712656-A | Oxazoline schiff base ligands and preparation method thereof | BEIJING INST TECHNOLOGY | 2010-05-26 | — | — | CN | disclosed |
| WO-2003016304-A1 | ORTHO-HETEROCYCLIC SUBSTITUTED ARYL AMIDES FOR CONTROLLING INVERTEBRATE PESTS | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 2003-02-27 | — | — | WO | disclosed |
| US-6316482-B1 | FOR THERAPY AND PROPHYLAXIS OF HYPERTENSION, HEART FAILURE, RENAL INSUFFICIENCY, EDEMA, ASCITES, VASOPRESSIN PARASECRETION SYNDROME, HEPATOCIRRHOSIS, HYPONATREMIA, HYPOKALEMIA, DIABETIC, CIRCULATION DISORDER, CEREBROVASCULAR DISEASE | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2001-11-13 | — | — | US | disclosed |
| US-6207693-B1 | Benzamide derivatives having a vasopressin antagonistic activity | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2001-03-27 | — | — | US | disclosed |
| EP-0946519-A1 | BENZAMIDE DERIVATIVES HAVING A VASOPRESSIN ANTAGONISTIC ACTIVITY | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1999-10-06 | — | — | EP | disclosed |
| WO-1998024771-A1 | BENZAMIDE DERIVATIVES HAVING A VASOPRESSIN ANTAGONISTIC ACTIVITY | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1998-06-11 | — | — | WO | disclosed |
| EP-0336391-B1 | Reversibly color-changeable materials | TEIJIN LTD (JP) | 1994-01-26 | — | — | EP | disclosed |
| US-5068062-A | Crosslinked resin containing 4,4*-diaminodiphenylmethane units with the amine quaternized and an electrolytic material | TEIJIN LIMITED (JP) | 1991-11-26 | — | — | US | disclosed |
| EP-0336391-A2 | Reversibly color-changeable materials | TEIJIN LIMITED (JP) | 1989-10-11 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-12441721-B2 | Synthesis of heterocyclic compounds from carboxamide and carboxamide derivatives with haloalkanols | NAAA, CNR2, AADAC | ALDH1A1 627/4885TDP1 2300/4885L3MBTL1 4591/4885 |
| US-20230295139-A1 | SYNTHESIS OF HETEROCYCLIC COMPOUNDS FROM CARBOXAMIDE AND CARBOXAMIDE DERIVATIVES WITH HALOALKANOLS | NAAA, CNR2, AADAC | ALDH1A1 627/4885TDP1 2300/4885L3MBTL1 4591/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.