Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.50 |
| ▸ | DPP4 | P27487 | 1/20 | 0.47 |
| ▸ | PBRM1 | Q86U86 | 1/20 | 0.46 |
| ▸ | TSHR | P16473 | 1/20 | 0.45 |
| ▸ | FEN1 | P39748 | 1/20 | 0.44 |
| ▸ | FABP3 | P05413 | 1/20 | 0.44 |
| ▸ | FABP4 | P15090 | 1/20 | 0.44 |
| ▸ | CA12 | O43570 | 1/20 | 0.41 |
| ▸ | CA1 | P00915 | 1/20 | 0.41 |
| ▸ | CA2 | P00918 | 1/20 | 0.41 |
| ▸ | CA7 | P43166 | 1/20 | 0.41 |
| ▸ | CA9 | Q16790 | 1/20 | 0.41 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.41 |
| ▸ | KLK1 | P06870 | 1/20 | 0.40 |
| ▸ | KLK5 | Q9Y337 | 1/20 | 0.40 |
| ▸ | TYK2 | P29597 | 1/20 | 0.40 |
| ▸ | TLR7 | Q9NYK1 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL80183 | 0.87 | ALDH1A1 (0.64) | ALDH1A1DPP4PBRM1TSHRFEN1 | |
| Hydrochloric Acid SCHEMBL8042412 | 0.84 | ALDH1A1 (0.61) | ALDH1A1DPP4PBRM1TSHRFEN1 | |
| SCHEMBL1041643 | 0.84 | ALDH1A1 (0.61) | ALDH1A1DPP4PBRM1TSHRFEN1 | |
| SCHEMBL7425018 | 0.84 | ALDH1A1 (0.61) | ALDH1A1DPP4PBRM1TSHRFEN1 | |
| SCHEMBL29031767 | 0.83 | ALDH1A1 (0.54) | ALDH1A1DPP4PBRM1TSHRFEN1 | |
| SCHEMBL784920 | 0.80 | TYK2 (0.55) | ALDH1A1DPP4TYK2 | |
| Trifluoroacetic Acid SCHEMBL15569989 | 0.78 | PBRM1 (0.50) | ALDH1A1PBRM1TYK2TLR7MEN1 | |
| SCHEMBL23908712 | 0.78 | ALDH1A1 (0.58) | ALDH1A1DPP4PBRM1TSHRFEN1 | |
| SCHEMBL29570977 | 0.77 | GAA (0.56) | ALDH1A1DPP4TYK2TLR7MEN1 | |
| SCHEMBL695459 | 0.77 | GAA (0.56) | ALDH1A1DPP4TYK2TLR7MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7511178-B2 | Hydroformylation of aqueous formaldehyde in the presence of a coordination catalyst preferably comprising rhodium dicarbonyl acetonylacetone and 2-phospha-2-icosyl-1,3,5,7-tetramethyl-6,9,10-trioxa-tricyclo[3.3.1.1{3,7}]-decane; hydrogenation of glycolaldehyde; catalyst selectivity; cost efficiency | SHELL OIL COMPANY (US) | 2009-03-31 | — | — | US | disclosed |
| US-20090012333-A1 | Hydroformylation of aqueous formaldehyde in the presence of a coordination catalyst preferably comprising rhodium dicarbonyl acetonylacetone and 2-phospha-2-icosyl-1,3,5,7-tetramethyl-6,9,10-trioxa-tricyclo[3.3.1.1{3,7}]-decane; hydrogenating glycolaldehyde; catalyst selectivity; cost efficiency | ALMEIDA LENERO KARINA QUETZALY | 2009-01-08 | — | — | US | disclosed |
| US-7449607-B2 | reacting formaldehyde with hydrogen and carbon monoxide in the presence of a catalyst comprising: a source of rhodium, and a ligand including a phospha-1,3,5,7-tetralkyl-6,9,10-trioxa-tricyclo[3.3.1.1{3,7}]-decyl group | SHELL OIL COMPANY (US) | 2008-11-11 | — | — | US | disclosed |
| US-20070249871-A1 | reacting formaldehyde with hydrogen and carbon monoxide in the presence of a catalyst comprising: a source of rhodium, and a ligand including a phospha-1,3,5,7-tetralkyl-6,9,10-trioxa-tricyclo[3.3.1.1{3,7}]-decyl group | SHELL OIL COMPANY (US) | 2007-10-25 | — | — | US | disclosed |
| EP-1697291-A1 | PROCESS FOR PREPARING GLYCOLALDEHYDE | SHELL INTERNATIONALE RESEARCHMAATSCHAPPIJ B.V. (NL) | 2006-09-06 | — | — | EP | disclosed |
| WO-2005058788-A1 | PROCESS OF PREPARING GLYCOLALDEHYDE | SHELL INTERNATIONALE RESEARCH MAATSCHAPPIJ B.V. (NL) | 2005-06-30 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090012333-A1 | Hydroformylation of aqueous formaldehyde in the presence of a coordination catalyst preferably comprising rhodium dicarbonyl acetonylacetone and 2-phospha-2-icosyl-1,3,5,7-tetramethyl-6,9,10-trioxa-tricyclo[3.3.1.1{3,7}]-decane; hydrogenating glycolaldehyde; catalyst selectivity; cost efficiency | H1-0, H1-2, H1-10 | ALDH1A1 117/4885DPP4 4517/4885PBRM1 1162/4885 |
| US-20070249871-A1 | reacting formaldehyde with hydrogen and carbon monoxide in the presence of a catalyst comprising: a source of rhodium, and a ligand including a phospha-1,3,5,7-tetralkyl-6,9,10-trioxa-tricyclo[3.3.1.1{3,7}]-decyl group | PHOSPHO1, H1-2, H1-0 | ALDH1A1 918/4885DPP4 4616/4885PBRM1 248/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.