SCHEMBL80183

SCHEMBL80183

O=C(O)c1c(Cl)cccc1Cl

nearest known ligand 0.64

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 4/20 0.64
DPP4 P27487 1/20 0.58
TSHR P16473 1/20 0.56
PBRM1 Q86U86 1/20 0.55
FEN1 P39748 1/20 0.54
CA12 O43570 2/20 0.52
CA1 P00915 2/20 0.52
CA2 P00918 2/20 0.52
CA7 P43166 2/20 0.52
CA9 Q16790 2/20 0.52
CA14 Q9ULX7 2/20 0.52
FABP3 P05413 1/20 0.52
FABP4 P15090 1/20 0.52
KDM4E B2RXH2 1/20 0.50
HSD17B10 Q99714 1/20 0.50
AKR1B1 P15121 1/20 0.50
HPGD P15428 2/20 0.47
NPC1 O15118 1/20 0.47
GLA P06280 1/20 0.47
KMT2A Q03164 2/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1041643 0.97 ALDH1A1 (0.61) ALDH1A1DPP4TSHRPBRM1FEN1
Hydrochloric Acid SCHEMBL8042412 0.97 ALDH1A1 (0.61) ALDH1A1DPP4TSHRPBRM1FEN1
SCHEMBL7425018 0.97 ALDH1A1 (0.61) ALDH1A1DPP4TSHRPBRM1FEN1
SCHEMBL29031767 0.91 ALDH1A1 (0.54) ALDH1A1DPP4TSHRPBRM1FEN1
SCHEMBL23908712 0.90 ALDH1A1 (0.58) ALDH1A1DPP4TSHRPBRM1FEN1
Benzoic Acid SCHEMBL28310499 0.89 TSHR (0.61) ALDH1A1DPP4TSHRPBRM1FABP3
Trifluoroacetic Acid SCHEMBL3979025 0.87 ALDH1A1 (0.50) ALDH1A1DPP4TSHRPBRM1FEN1
SCHEMBL330729 0.85 CA12 (0.70) ALDH1A1DPP4TSHRPBRM1FEN1
SCHEMBL31356504 0.85 TSHR (0.65) ALDH1A1DPP4TSHRPBRM1FEN1
SCHEMBL275485 0.85 TSHR (0.65) ALDH1A1DPP4TSHRPBRM1FEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1370 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-119638293-A Production method of environment-friendly light calcium silicate board 山东连银山环保建材有限公司 2025-03-18 CN claimed
CN-119552359-A Cation modified polyimide resin and preparation method thereof 江苏集萃功能材料研究所有限公司 2025-03-04 CN claimed
CN-119431308-A Diamine monomer, self-repairing thermoplastic polyimide resin and preparation method thereof 江苏集萃功能材料研究所有限公司 2025-02-14 CN claimed
CN-119409981-A Cadmium coordination polymer capable of regulating and controlling photo-stimulus response behavior through thermal phase change, and preparation method and application thereof 广西民族大学 2025-02-11 CN claimed
CN-118754816-B Preparation method of diclofenac sodium 世华合创生物技术开发(山东)有限公司 2024-12-20 CN claimed
CN-115894330-B Synthesis method and application of 1-acetyl-1H-indol-3-yl acetate derivative 吉林医药学院 2024-12-10 CN claimed
CN-118754816-A Preparation method of diclofenac sodium 世华合创生物技术开发(山东)有限公司 2024-10-11 CN claimed
CN-118491709-A Beneficiation reagent for recovering tin from iron-tin ore and preparation method thereof 西北矿冶研究院 2024-08-16 CN claimed
CN-118165020-A Hyperbranched boron phenolic monomer and shape memory boron phenolic resin 哈尔滨工业大学 2024-06-11 CN claimed
CN-117603604-B Preparation method of printing gloss oil with amino-terminated hyperbranched self-assembled polyamide as main component 江苏众立生包装科技有限公司 2024-05-24 CN claimed
EP-0520815-A2 Method for producing ortho-alkoxybenzoic acid NIPPON CHEMICAL INDUSTRIAL COMPANY LIMITED (JP) 1992-12-30 EP claimed
EP-0271145-B1 PROCESS FOR THE CARBONYLATION OF CONJUGATED DIENES SHELL INTERNATIONALE RESEARCHMAATSCHAPPIJ B.V. (NL) 1991-08-21 EP claimed
EP-0235864-B1 PROCESS FOR THE CARBONYLATION OF OLEFINICALLY UNSATURATED COMPOUNDS WITH A PALLADIUM CATALYST SHELL INTERNATIONALE RESEARCHMAATSCHAPPIJ B.V. (NL) 1990-05-16 EP claimed
EP-0224292-B1 PROCESS FOR THE PREPARATION OF ORGANIC ISOCYANATES SHELL INTERNATIONALE RESEARCHMAATSCHAPPIJ B.V. (NL) 1990-04-11 EP claimed
US-4824817-A Catalyst for the carbonylation of conjugated dienes SHELL OIL COMPANY (US) 1989-04-25 US claimed
EP-0271145-A2 Process for the carbonylation of conjugated dienes SHELL INTERNATIONALE RESEARCHMAATSCHAPPIJ B.V. (NL) 1988-06-15 EP claimed
CN-87107284-A Process for the carbonylation of conjugated dienes 1988-06-15 CN claimed
EP-0235864-A1 Process for the carbonylation of olefinically unsaturated compounds with a palladium catalyst SHELL INTERNATIONALE RESEARCHMAATSCHAPPIJ B.V. (NL) 1987-09-09 EP claimed
EP-0228564-A2 Novel insecticidal diacylhydrazine compounds AMERICAN CYANAMID COMPANY (US) 1987-07-15 EP claimed
US-4154921-A REDUCE FORMATION OF SCALE BY ADDITION OF A HINDERED BENZOIC ACID INCLUDING 2,6-DICHLORO-, 2,6-DIMETHYL-, AND 2,4,6-TRIMETHYL-/; E. I. DU PONT DE NEMOURS AND COMPANY (US) 1979-05-15 US claimed