Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CISD1 | Q9NZ45 | 8/20 | 0.38 |
| ▸ | PLK1 | P53350 | 4/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | RARB | P10826 | 1/20 | 0.33 |
| ▸ | RPS6KB1 | P23443 | 1/20 | 0.33 |
| ▸ | KDM6B | O15054 | 1/20 | 0.33 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3973224 | 0.93 | CISD1 (0.36) | CISD1PLK1MEN1TSHRKMT2A | |
| SCHEMBL2428070 | 0.83 | MEN1 (0.47) | CISD1MEN1TSHRKMT2AKDM6B | |
| SCHEMBL2426202 | 0.81 | CISD1 (0.52) | CISD1PLK1KDM6BKDM4C | |
| SCHEMBL4258452 | 0.81 | MEN1 (0.34) | CISD1MEN1TSHRKMT2AKDM6B | |
| SCHEMBL2431005 | 0.79 | CISD1 (0.49) | CISD1PLK1KDM6BKDM4C | |
| SCHEMBL3975210 | 0.76 | CASR (0.33) | PLK1MEN1TSHRKMT2AKDM6B | |
| SCHEMBL11578119 | 0.75 | MAPT (0.38) | — | |
| SCHEMBL2424142 | 0.75 | HSP90AA1 (0.46) | — | |
| SCHEMBL2426568 | 0.75 | HSP90AA1 (0.46) | — | |
| SCHEMBL2424139 | 0.75 | HSP90AA1 (0.46) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2074120-A1 | TROPANE COMPOUNDS | Exelixis, Inc. (US) | 2009-07-01 | — | — | EP | disclosed |
| WO-2009055077-A1 | TROPANE COMPOUNDS | EXELIXIS, INC. (US) | 2009-04-30 | — | — | WO | disclosed |