SCHEMBL3979211

SCHEMBL3979211

ONC1Cc2ccccc2C=N1

nearest known ligand 0.35

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
TRPA1 O75762 5/20 0.35
IDO1 P14902 2/20 0.31
CYP19A1 P11511 1/20 0.30
CYP11B1 P15538 1/20 0.30
CYP11B2 P19099 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28300490 0.77 TRPA1 (0.33) TRPA1
SCHEMBL27453351 0.73 HDAC4 (0.42)
SCHEMBL28173156 0.71 TRPA1 (0.38) TRPA1IDO1CYP19A1CYP11B1CYP11B2
SCHEMBL27729037 0.71 TRPA1 (0.38) TRPA1IDO1CYP19A1CYP11B1CYP11B2
SCHEMBL18464841 0.71 TRPA1 (0.38) TRPA1IDO1CYP19A1CYP11B1CYP11B2
SCHEMBL31303677 0.71 NOS3 (0.43) TRPA1IDO1CYP19A1CYP11B1CYP11B2
SCHEMBL28139071 0.71 NOS3 (0.43) TRPA1IDO1CYP19A1CYP11B1CYP11B2
SCHEMBL5008439 0.71 NOS3 (0.43) TRPA1IDO1CYP19A1CYP11B1CYP11B2
SCHEMBL8628901 0.70 TRPA1 (0.35) TRPA1IDO1CYP19A1CYP11B1CYP11B2
SCHEMBL31168159 0.70 TRPA1 (0.35) TRPA1IDO1CYP19A1CYP11B1CYP11B2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2009058287-A1 PROCESS OF PURIFICATION OF AMIDOXIME CONTAINING CLEANING SOLUTIONS AND THEIR USE EKC TECHNOLOGY, INC. (US) 2009-05-07 WO disclosed