Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 2/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | ATM | Q13315 | 1/20 | 0.43 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.42 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.42 |
| ▸ | PNMT | P11086 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | CA1 | P00915 | 1/20 | 0.42 |
| ▸ | CA2 | P00918 | 1/20 | 0.42 |
| ▸ | ACHE | P22303 | 1/20 | 0.42 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.42 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.42 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | GLA | P06280 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2252742 | 1.00 | SMN1; SMN2 (0.44) | SMN1; SMN2MEN1KMT2AATMCYP2D6 | |
| SCHEMBL4100987 | 1.00 | SMN1; SMN2 (0.44) | SMN1; SMN2MEN1KMT2AATMCYP2D6 | |
| Hydrochloric Acid SCHEMBL3660925 | 0.98 | ALDH1A1 (0.44) | SMN1; SMN2MEN1KMT2AATMCYP2D6 | |
| Hydrochloric Acid SCHEMBL3700107 | 0.98 | ALDH1A1 (0.44) | SMN1; SMN2MEN1KMT2AATMCYP2D6 | |
| SCHEMBL683593 | 0.83 | NFE2L2 (0.47) | SMN1; SMN2MEN1KMT2AATMCYP1A2 | |
| SCHEMBL29471011 | 0.83 | CA1 (0.55) | MEN1KMT2ACYP2D6CYP1A2CYP3A4 | |
| SCHEMBL29705638 | 0.83 | CA1 (0.55) | MEN1KMT2ACYP2D6CYP1A2CYP3A4 | |
| SCHEMBL1257092 | 0.83 | CA1 (0.55) | MEN1KMT2ACYP2D6CYP1A2CYP3A4 | |
| SCHEMBL21377269 | 0.83 | CA1 (0.55) | MEN1KMT2ACYP2D6CYP1A2CYP3A4 | |
| SCHEMBL334556 | 0.83 | CA1 (0.55) | MEN1KMT2ACYP2D6CYP1A2CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009056993-A2 | A PROCESS FOR THE SYNTHESIS OF RAMELTEON AND ITS INTERMEDIATES | TEVA PHARMACEUTICAL INDUSTRIES LTD. (IL) | 2009-05-07 | — | — | WO | claimed |