Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F2R | P25116 | 17/20 | 0.99 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Bromide SCHEMBL1730399 | 0.99 | F2R (1.00) | F2RALDH1A1GAA | |
| SCHEMBL13628887 | 0.93 | F2R (0.88) | F2RALDH1A1GAA | |
| SCHEMBL1730720 | 0.91 | F2R (0.99) | F2RALDH1A1GAA | |
| SCHEMBL14468855 | 0.91 | F2R (0.82) | F2RALDH1A1GAA | |
| Hydrochloric Acid SCHEMBL1728724 | 0.91 | F2R (1.00) | F2RALDH1A1GAA | |
| SCHEMBL13950221 | 0.91 | F2R (0.85) | F2R | |
| SCHEMBL14449152 | 0.91 | F2R (0.87) | F2RGAA | |
| SCHEMBL13038490 | 0.90 | F2R (0.85) | F2RALDH1A1GAA | |
| SCHEMBL13637742 | 0.90 | F2R (0.83) | F2RALDH1A1GAA | |
| SCHEMBL9989475 | 0.90 | F2R (0.85) | F2RALDH1A1GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 19 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8658620-B2 | Pharmaceutical composition, use of 2-iminopyrrolidine derivative for production of pharmaceutical composition, and kit for treatment or amelioration of heart diseases | EISAI R&D MANAGEMENT CO., LTD. (JP) | 2014-02-25 | — | — | US | disclosed |
| US-8658620-B2 | Pharmaceutical composition, use of 2-iminopyrrolidine derivative for production of pharmaceutical composition, and kit for treatment or amelioration of heart diseases | EISAI R&D MANAGEMENT CO., LTD. (JP) | 2014-02-25 | — | — | US | disclosed |
| US-20100286087-A1 | PHARMACEUTICAL COMPOSITION, USE OF 2-IMINOPYRROLIDINE DERIVATIVE FOR PRODUCTION OF PHARMACEUTICAL COMPOSITION, AND KIT FOR TREATMENT OR AMELIORATION OF HEART DISEASES | EISAI R&D MANAGEMENT CO, LTD. (JP) | 2010-11-11 | — | — | US | disclosed |
| US-20100286087-A1 | PHARMACEUTICAL COMPOSITION, USE OF 2-IMINOPYRROLIDINE DERIVATIVE FOR PRODUCTION OF PHARMACEUTICAL COMPOSITION, AND KIT FOR TREATMENT OR AMELIORATION OF HEART DISEASES | EISAI R&D MANAGEMENT CO, LTD. (JP) | 2010-11-11 | — | — | US | disclosed |
| US-20100063048-A1 | Remedy for angiospasm accompanying subarachnoid hemorrhage containing thrombin receptor antagonist as the active ingredient | Eisai R&D Mangement Co., Ltd. (JP) | 2010-03-11 | — | — | US | disclosed |
| US-7612066-B2 | Composition containing benzamidine derivative and method for stabilizing benzamidine derivative | EISAI R&D MANAGEMENT CO., LTD. (JP) | 2009-11-03 | — | — | US | disclosed |
| US-7612066-B2 | Composition containing benzamidine derivative and method for stabilizing benzamidine derivative | EISAI R&D MANAGEMENT CO., LTD. (JP) | 2009-11-03 | — | — | US | disclosed |
| US-7612066-B2 | Composition containing benzamidine derivative and method for stabilizing benzamidine derivative | EISAI R&D MANAGEMENT CO., LTD. (JP) | 2009-11-03 | — | — | US | disclosed |
| EP-1721610-B1 | COMPOSITION CONTAINING BENZAMIDINE DERIVATIVE AND METHOD FOR STABILIZING BENZAMIDINE DERIVATIVE | EISAI R&D MAN CO LTD (JP) | 2009-05-13 | — | — | EP | disclosed |
| EP-1721610-B1 | COMPOSITION CONTAINING BENZAMIDINE DERIVATIVE AND METHOD FOR STABILIZING BENZAMIDINE DERIVATIVE | EISAI R&D MAN CO LTD (JP) | 2009-05-13 | — | — | EP | disclosed |
| US-20090022729-A1 | METHODS AND COMPOSITIONS FOR TREATING CARDIAC DYSFUNCTIONS | NATIONAL INSTITUTES OF HEALTH - DIRECTOR DEITR | 2009-01-22 | — | — | US | disclosed |
| US-20090022729-A1 | METHODS AND COMPOSITIONS FOR TREATING CARDIAC DYSFUNCTIONS | NATIONAL INSTITUTES OF HEALTH - DIRECTOR DEITR | 2009-01-22 | — | — | US | disclosed |
| US-20080194559-A1 | Remedy for Angiospasm Accompanying Subarachnoid Hemorrhage Containing Thrombin Receptor Antagonist as the Active Ingredient | EISAI R.& D MANAGMENT CO., LTD. (JP) | 2008-08-14 | — | — | US | disclosed |
| US-20080194559-A1 | Remedy for Angiospasm Accompanying Subarachnoid Hemorrhage Containing Thrombin Receptor Antagonist as the Active Ingredient | EISAI R.& D MANAGMENT CO., LTD. (JP) | 2008-08-14 | — | — | US | disclosed |
| US-20070208016-A1 | Composition Containing Benzamidine Derivative and Method For Stabilizing Benzamidine Derivative | EISAI R&D MANAGEMENT CO., LTD. (JP) | 2007-09-06 | — | — | US | disclosed |
| US-20070208016-A1 | Composition Containing Benzamidine Derivative and Method For Stabilizing Benzamidine Derivative | EISAI R&D MANAGEMENT CO., LTD. (JP) | 2007-09-06 | — | — | US | disclosed |
| US-20070208016-A1 | Composition Containing Benzamidine Derivative and Method For Stabilizing Benzamidine Derivative | EISAI R&D MANAGEMENT CO., LTD. (JP) | 2007-09-06 | — | — | US | disclosed |
| US-7244730-B2 | 2-iminopyrrolidine derivatives | EISAI CO., LTD (JP) | 2007-07-17 | — | — | US | disclosed |
| EP-1721610-A1 | COMPOSITION CONTAINING BENZAMIDINE DERIVATIVE AND METHOD FOR STABILIZING BENZAMIDINE DERIVATIVE | Eisai R&D Management Co., Ltd. (JP) | 2006-11-15 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100063048-A1 | Remedy for angiospasm accompanying subarachnoid hemorrhage containing thrombin receptor antagonist as the active ingredient | F2R, F2RL1, PLAT | F2R 1/4885ALDH1A1 3097/4885GAA 2143/4885 |
| US-20070208016-A1 | Composition Containing Benzamidine Derivative and Method For Stabilizing Benzamidine Derivative | CMA1, DDC, GBA1 | F2R 4361/4885ALDH1A1 467/4885GAA 44/4885 |
| US-20090022729-A1 | METHODS AND COMPOSITIONS FOR TREATING CARDIAC DYSFUNCTIONS | TNNI3, MYLK2, FABP3 | F2R 8/4885ALDH1A1 2037/4885GAA 3197/4885 |
| US-20100286087-A1 | PHARMACEUTICAL COMPOSITION, USE OF 2-IMINOPYRROLIDINE DERIVATIVE FOR PRODUCTION OF PHARMACEUTICAL COMPOSITION, AND KIT FOR TREATMENT OR AMELIORATION OF HEART DISEASES | KIT, TNNT2, TNNI3 | F2R 1051/4885ALDH1A1 535/4885GAA 1429/4885 |
| US-20080194559-A1 | Remedy for Angiospasm Accompanying Subarachnoid Hemorrhage Containing Thrombin Receptor Antagonist as the Active Ingredient | F2R, F2RL1, PLAT | F2R 1/4885ALDH1A1 3088/4885GAA 2406/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.