SCHEMBL397973

SCHEMBL397973

Nc1cc(C(=O)O)ccc1F

nearest known ligand 0.58

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 10/20 0.58
GAA P10253 8/20 0.58
HSD17B10 Q99714 5/20 0.58
GFER P55789 3/20 0.58
MEN1 O00255 1/20 0.58
KMT2A Q03164 1/20 0.58
CDC25B P30305 1/20 0.50
MAPT P10636 5/20 0.49
ALDH1A1 P00352 4/20 0.49
THRB P10828 3/20 0.49
HPGD P15428 3/20 0.49
HTT P42858 2/20 0.49
PLEC Q15149 1/20 0.49
LMNA P02545 3/20 0.48
MAPK1 P28482 1/20 0.48
RAB9A P51151 1/20 0.48
L3MBTL1 Q9Y468 3/20 0.47
POLB P06746 2/20 0.47
TDP1 Q9NUW8 2/20 0.47
TP53 P04637 1/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29475726 1.00 KDM4E (0.58) KDM4EGAAHSD17B10GFERMEN1
SCHEMBL7142180 0.86 KDM4E (0.48) KDM4EGAAHSD17B10GFERMEN1
SCHEMBL8013848 0.84 GAA (0.52) KDM4EGAAHSD17B10GFERMEN1
SCHEMBL7162401 0.83 CES2 (0.52) KDM4EGAAHSD17B10GFERMEN1
Hydrochloric Acid SCHEMBL8752684 0.83 GAA (0.50) KDM4EGAAHSD17B10GFERMEN1
SCHEMBL3078849 0.83 PARP1 (0.50) KDM4EGAAHSD17B10GFERMEN1
Ammonia Solution, Strong SCHEMBL8752682 0.83 GAA (0.50) KDM4EGAAHSD17B10GFERMEN1
SCHEMBL8752661 0.83 MAPT (0.50) KDM4EGAAHSD17B10GFERMEN1
SCHEMBL97816 0.83 HDAC1 (0.63) KDM4EGAAHSD17B10GFERMEN1
SCHEMBL29367661 0.83 HDAC1 (0.63) KDM4EGAAHSD17B10GFERMEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 355 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-117800914-B Anti-SARS-CoV-2 virus armstrong mutant inhibitor 中国人民解放军海军军医大学 2026-05-19 CN claimed
CN-119320592-B High-weather-resistance self-cleaning nano silicon coating and preparation process thereof 云南云岭涂料有限公司 2025-05-13 CN claimed
CN-119320592-A High-weather-resistance self-cleaning nano silicon coating and preparation process thereof 云南云岭涂料有限公司 2025-01-17 CN claimed
CN-116606257-A Preparation process of intermediate 7-chloro 8-quinolinic acid and synthesis process of quinclorac 启农生物科技(北京)有限公司 2023-08-18 CN claimed
CN-115974791-A Preparation process of intermediate I for synthesizing saflufenacil 启农生物科技(北京)有限公司 2023-04-18 CN claimed
CN-104530107-B A kind of synthetic method of 3-amino-4-fluorobenzoic boric acid 大连联化化学有限公司 2016-08-24 CN claimed
CN-103626791-B A kind of method of synthesizing 3-amino-4-fluorobenzoic boric acid LIANHUA CHEMISTRY Co.,Ltd. DALIAN (CN) 2016-04-06 CN claimed
CN-104530107-A Synthetic method for 3-amino-4-fluorophenylboronic acid LIANHUA CHEMISTRY CO LTD DALIAN 2015-04-22 CN claimed
CN-103626791-A Method for synthesizing 3-amino-4-fluorophenylboronic acid LIANHUA CHEMISTRY CO LTD DALIAN 2014-03-12 CN claimed
US-20260144743-A1 COMPOUNDS TMEM16A LIMITED (GB) 2026-05-28 US disclosed
CN-117800914-B Anti-SARS-CoV-2 virus armstrong mutant inhibitor 中国人民解放军海军军医大学 2026-05-19 CN disclosed
EP-4166557-B1 INTERMEDIATES OF N-(3-(7H-PYRROLO[2,3-D]PYRIMIDIN-4-YL)PHENYL)BENZAMIDE DERIVATIVES NOVARTIS AG (CH) 2026-05-06 EP disclosed
US-12569566-B2 Compositions containing, methods and uses of antibody-TLR agonist conjugates AMBRX, INC. (US) 2026-03-10 US disclosed
EP-4699655-A2 COMPOUNDS TMEM16A LIMITED (GB) 2026-02-25 EP disclosed
EP-0356080-B1 Anionic dye ZENECA LTD (GB) 1994-06-08 EP disclosed
US-5262527-A Disazo dyes suitable for use in ink jet printing IMPERIAL CHEMICAL INDUSTRIES PLC (GB) 1993-11-16 US disclosed
US-4929272-A N-phenyl-maleimides and N-phenyl-succinimides and their use in a herbicidal and/or plant growth regulating action CIBA-GEIGY CORPORATION (US) 1990-05-29 US disclosed
US-4804400-A PRE- AND POSTEMERGENCE; GRAINS CIBA-GEIGY CORPORATION (US) 1989-02-14 US disclosed
EP-0260228-A2 N-phenyl-malein imides and N-phenyl-succinimides with a herbicidal and a plant growth regulation activity CIBA-GEIGY AG (CH) 1988-03-16 EP disclosed
US-4065448-A Tertiary alkyl substituted disazo pigments CIBA-GEIGY AG (CH) 1977-12-27 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20260144743-A1 COMPOUNDS CACNA1E, TMEM109, CACNA1C KDM4E 3794/4885GAA 1568/4885HSD17B10 868/4885
US-12569566-B2 Compositions containing, methods and uses of antibody-TLR agonist conjugates TLR3, TLR2, TLR1 KDM4E 125/4885GAA 2983/4885HSD17B10 1843/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.