Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3634409 | 0.76 | BDKRB1 (0.36) | — | |
| SCHEMBL3229309 | 0.73 | — | — | |
| SCHEMBL2568687 | 0.72 | GRM5 (0.33) | ALDH1A1 | |
| SCHEMBL4729458 | 0.70 | TRPV4 (0.37) | ALDH1A1 | |
| SCHEMBL29649716 | 0.69 | TRPV4 (0.40) | ALDH1A1 | |
| SCHEMBL17586504 | 0.69 | TRPV4 (0.40) | ALDH1A1 | |
| SCHEMBL23262834 | 0.67 | GRM5 (0.35) | ALDH1A1 | |
| SCHEMBL16132531 | 0.67 | HSD11B1 (0.37) | — | |
| SCHEMBL18463843 | 0.67 | TRPV4 (0.34) | ALDH1A1 | |
| SCHEMBL22601464 | 0.67 | TRPV4 (0.39) | ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009056886-A1 | PYRIMIDINE DERIVATIVES AND THEIR USE AS MODULATORS OF FGFR ACTIVITY | ASTRAZENECA AB (SE) | 2009-05-07 | — | — | WO | disclosed |