⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3979899 | 0.73 | ALDH1A1 (0.32) | — | |
| SCHEMBL4340769 | 0.73 | GABRA5 (0.33) | — | |
| SCHEMBL3634409 | 0.72 | BDKRB1 (0.36) | — | |
| SCHEMBL2568687 | 0.71 | GRM5 (0.33) | — | |
| SCHEMBL16019424 | 0.70 | TRPV4 (0.34) | — | |
| SCHEMBL4729458 | 0.69 | TRPV4 (0.37) | — | |
| SCHEMBL29649716 | 0.68 | TRPV4 (0.40) | — | |
| SCHEMBL17586504 | 0.68 | TRPV4 (0.40) | — | |
| SCHEMBL3238364 | 0.68 | HDAC6 (0.41) | — | |
| SCHEMBL346024 | 0.68 | HDAC6 (0.41) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010020810-A1 | 2-(IMIDAZ0LYLAMIN0)-PYRIDINE DERIVATIVES AND THEIR USE AS JAK KINASE INHIBITORS | ASTRAZENECA AB (SE) | 2010-02-25 | — | — | WO | disclosed |