SCHEMBL3979932

SCHEMBL3979932

Cc1cccc(-c2ccc(O)cc2C(C)(C)C)c1-c1ccc(O)cc1C(C)(C)C

nearest known ligand 0.46

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 4/20 0.46
HSD17B10 Q99714 3/20 0.46
LMNA P02545 2/20 0.46
NR1I2 O75469 1/20 0.46
CYP2C9 P11712 1/20 0.46
MIF P14174 1/20 0.46
TYR P14679 1/20 0.46
ALOX15 P16050 1/20 0.46
HTT P42858 1/20 0.46
NFE2L2 Q16236 1/20 0.46
GABRA1 P14867 1/20 0.44
GABRB2 P47870 1/20 0.44
ANPEP P15144 1/20 0.39
DPP4 P27487 1/20 0.39
ESR2 Q92731 4/20 0.39
CYP1A2 P05177 1/20 0.37
CYP2C19 P33261 1/20 0.37
CA2 P00918 2/20 0.37
ACHE P22303 1/20 0.37
CNR1 P21554 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7946600 0.86 GABRA1 (0.47) ALDH1A1HSD17B10LMNANR1I2CYP2C9
SCHEMBL29091704 0.85 ALDH1A1 (0.52) ALDH1A1HSD17B10LMNANR1I2CYP2C9
SCHEMBL7948453 0.81 GABRA1 (0.42) ALDH1A1HSD17B10LMNANR1I2CYP2C9
SCHEMBL7858673 0.80 ALDH1A1 (0.67) ALDH1A1HSD17B10LMNANR1I2CYP2C9
SCHEMBL30629387 0.80 ALDH1A1 (0.67) ALDH1A1HSD17B10LMNANR1I2CYP2C9
SCHEMBL4064185 0.79 GABRA1 (0.46) ALDH1A1HSD17B10LMNANR1I2CYP2C9
SCHEMBL8039251 0.78 MGAM (0.46) ALDH1A1HSD17B10LMNATYRANPEP
SCHEMBL9176175 0.77 ALDH1A1 (0.48) ALDH1A1HSD17B10LMNANR1I2CYP2C9
SCHEMBL7848525 0.77 ALDH1A1 (0.57) ALDH1A1HSD17B10LMNANR1I2CYP2C9
SCHEMBL7948439 0.77 PDK2 (0.38) ALDH1A1HSD17B10LMNANR1I2CYP2C9

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1469026-B1 AROMATIC POLYCARBONATE RESIN PROCESS FOR PRODUCING THE SAME OPTICAL PART MOLDING MATERIAL AND OPTICAL PART IDEMITSU KOSAN CO (JP) 2009-05-06 EP disclosed
US-7329718-B2 Aromatic polycarbonate resin, process for producing the same, optical-part molding material, and optical part IDEMITSU KOSAN CO., LTD. (JP) 2008-02-12 US disclosed
US-20060270823-A1 Suited to a molding material for an optical disc substrate such as a digital audio disc, a digital video disc and an optical memory disc, various lenses such as a lens for an optical pickup, spectacle lenses, contact lenses and a lens sheet, an optical sheet substrate IDEMITSU KOSAN CO., LTD (JP) 2006-11-30 US disclosed
US-7112644-B2 Aromatic polycarbonate resin, process for producing the same, optical-part molding material, and optical part IDEMITSU KOSAN CO., LTD. (JP) 2006-09-26 US disclosed
EP-1361241-B1 Process for producing raw polycarbonate resin material and producing polycarbonate resin IDEMITSU KOSAN CO (JP) 2005-08-24 EP disclosed
US-20050143553-A1 Aromatic polycarbonate resin, process for producing the same, optical-part molding material, and optical part IDEMITSU KOSAN CO., LTD (JP) 2005-06-30 US disclosed
EP-1178068-B1 PROCESSES FOR PRODUCING RAW POLYCARBONATE RESIN MATERIAL AND PRODUCING POLYCARBONATE RESIN IDEMITSU KOSAN CO (JP) 2005-05-18 EP disclosed
EP-1469026-A1 AROMATIC POLYCARBONATE RESIN PROCESS FOR PRODUCING THE SAME OPTICAL PART MOLDINGMATERIAL AND OPTICAL PART IDEMITSU KOSAN CO., LTD. (JP) 2004-10-20 EP disclosed
EP-1361241-A1 Process for producing raw polycarbonate resin material and producing polycarbonate resin IDEMITSU PETROCHEMICAL CO., LTD. (JP) 2003-11-12 EP disclosed
EP-1178068-A1 PROCESSES FOR PRODUCING RAW POLYCARBONATE RESIN MATERIAL AND PRODUCING POLYCARBONATE RESIN IDEMITSU PETROCHEMICAL CO., LTD. (JP) 2002-02-06 EP disclosed