Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 4/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | PGD | P52209 | 2/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | RNPEP | Q9H4A4 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30616867 | 1.00 | TSHR (0.46) | TSHRALDH1A1TP53HTTPGD | |
| SCHEMBL5481281 | 0.91 | TSHR (0.50) | TSHRALDH1A1HTTRAB9ASMN1; SMN2 | |
| SCHEMBL8636456 | 0.91 | TSHR (0.50) | TSHRALDH1A1HTTRAB9ASMN1; SMN2 | |
| SCHEMBL7773088 | 0.86 | TSHR (0.46) | TSHRTP53HTTPGD | |
| SCHEMBL537156 | 0.86 | TSHR (0.46) | TSHRTP53HTTPGD | |
| SCHEMBL2953433 | 0.86 | TSHR (0.37) | TSHRALDH1A1TP53HTTPGD | |
| Ether SCHEMBL2956578 | 0.86 | TSHR (0.34) | TSHRALDH1A1SMN1; SMN2 | |
| SCHEMBL15512566 | 0.85 | TSHR (0.40) | TSHRTP53HTTPGD | |
| Ether SCHEMBL2960153 | 0.83 | TSHR (0.36) | TSHRALDH1A1 | |
| SCHEMBL2962715 | 0.82 | TSHR (0.37) | TSHRALDH1A1TP53HTTPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 27 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-106349089-B | Method for extracting and separating metoprolol enantiomer by adopting tartrate-polyacid complex | 湖南理工学院 | 2021-04-02 | — | — | CN | claimed |
| CN-106349089-A | Method using tartrate-polybasic acid complex to extract and separate metoprolol enantiomer | 湖南理工学院 | 2017-01-25 | — | — | CN | claimed |
| CN-103922877-B | Double-aqueous phase system chiral separation Omprazole compound | 湖南如虹制药有限公司 | 2016-07-06 | — | — | CN | claimed |
| CN-103951653-B | The method of two-phase identification fractional extraction separation pantoprazole sodium enantiomers | 湖南理工学院 | 2016-06-29 | — | — | CN | claimed |
| CN-104277030-B | A kind of reaction, extraction is separated the method for pantoprazole enantiomers | HUNAN TECHNOLOGY COLLEGE (CN) | 2016-04-20 | — | — | CN | claimed |
| CN-103951653-A | Method for performing two-phase recognizing, fractionating, extracting and separating on pantoprazole sodium enantiomer | HUNAN INST SCIENCE & TECH | 2014-07-30 | — | — | CN | claimed |
| CN-103922877-A | Chiral resolution of prazole compound by aqueous two-phase system | HUNAN RHON PHARMACEUTICAL CO LTD | 2014-07-16 | — | — | CN | claimed |
| CN-102001904-A | Novel chiral separation method | HUNAN INST SCIENCE & TECH | 2011-04-06 | — | — | CN | claimed |
| US-20230339839-A1 | SYNTHESIS METHOD OF ALPHA-HYDROXYCARBOXYLIC ACID ESTER | Guangxi Forestry Research Institute (CN) | 2023-10-26 | — | — | US | disclosed |
| CN-112724103-A | Isopromazine specific impurity and analysis method and removal method thereof | 广安凯特制药有限公司 | 2021-04-30 | — | — | CN | disclosed |
| CN-106349089-B | Method for extracting and separating metoprolol enantiomer by adopting tartrate-polyacid complex | 湖南理工学院 | 2021-04-02 | — | — | CN | disclosed |
| CN-106349089-A | Method using tartrate-polybasic acid complex to extract and separate metoprolol enantiomer | 湖南理工学院 | 2017-01-25 | — | — | CN | disclosed |
| CN-103951653-B | The method of two-phase identification fractional extraction separation pantoprazole sodium enantiomers | 湖南理工学院 | 2016-06-29 | — | — | CN | disclosed |
| CN-103951653-B | The method of two-phase identification fractional extraction separation pantoprazole sodium enantiomers | 湖南理工学院 | 2016-06-29 | — | — | CN | disclosed |
| US-20070275022-A1 | Cosmetic Hair Preparation | LION CORPORATION (JP) | 2007-11-29 | — | — | US | disclosed |
| US-20060281692-A1 | Use of derivatives of succinate esters for the treatment of dementia | BEIJING LIANXIN PHARMACEUTIC CO., LTD. (CN) | 2006-12-14 | — | — | US | disclosed |
| CN-1731991-A | Use of succinic acid derivative ester compounds for treating dementia | INST MATERIA MEDICA CAMS (CN) | 2006-02-08 | — | — | CN | disclosed |
| CN-1712057-A | Preparation of succinic acid carbobenzoxy derivative of orchid family plant effective part | DRUG INST CHINESE ACADEMY OF M (CN) | 2005-12-28 | — | — | CN | disclosed |
| EP-1582209-A1 | THE USE OF SUCCINATE DERIVATIVE ESTERS FOR THE TREATMENT OF DEMENTIA | THE INSTITUTE OF MATERIA MEDICA OF CHINESE ACADEMY OF MEDICAL SCIENCES (CN) | 2005-10-05 | — | — | EP | disclosed |
| CN-1511520-A | Use of succinate derivative for biologically treating dementia | �й�ҽѧ��ѧԺҩ���о��� | 2004-07-14 | — | — | CN | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070275022-A1 | Cosmetic Hair Preparation | CUTA, H1-10, PUF60 | TSHR 3396/4885ALDH1A1 1020/4885TP53 1184/4885 |
| US-20060281692-A1 | Use of derivatives of succinate esters for the treatment of dementia | BCHE, ACHE, SI | TSHR 4795/4885ALDH1A1 3854/4885TP53 1177/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.