Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACE | P12821 | 10/20 | 0.40 |
| ▸ | REN | P00797 | 4/20 | 0.40 |
| ▸ | LMNA | P02545 | 2/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | F2 | P00734 | 1/20 | 0.40 |
| ▸ | LTA4H | P09960 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | PEPD | P12955 | 1/20 | 0.40 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.40 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.40 |
| ▸ | HTR2A | P28223 | 1/20 | 0.40 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.40 |
| ▸ | HRH1 | P35367 | 1/20 | 0.40 |
| ▸ | THPO | P40225 | 1/20 | 0.40 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
| ▸ | ACE2 | Q9BYF1 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2289363 | 0.88 | ELANE (0.42) | — | |
| SCHEMBL230923 | 0.85 | ELANE (0.33) | — | |
| SCHEMBL8662040 | 0.85 | ELANE (0.40) | — | |
| SCHEMBL228960 | 0.83 | ELANE (0.38) | — | |
| SCHEMBL5487413 | 0.83 | ELANE (0.38) | — | |
| SCHEMBL847832 | 0.82 | CMA1 (0.49) | ACEREN | |
| SCHEMBL3276266 | 0.82 | ELANE (0.42) | — | |
| SCHEMBL398010 | 0.79 | KCNH2 (0.39) | LMNA | |
| SCHEMBL387694 | 0.77 | TACR1 (0.40) | LMNA | |
| SCHEMBL1800549 | 0.76 | ACE (0.42) | ACERENLMNAKDM4EF2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10501780-B2 | Compositions for in situ nucleic acid analysis | APPLIED BIOSYSTEMS, LLC (US) | 2019-12-10 | — | — | US | disclosed |
| US-20160230220-A1 | SAMPLE PREPARATION FOR IN SITU NUCLEIC ACID ANALYSIS, METHODS AND COMPOSITIONS THEREFOR | APPLERA CORPORATION | 2016-08-11 | — | — | US | disclosed |
| EP-2414512-A1 | ENHANCED PRODUCTION OF PAPILLOMAVIRUS-LIKE PARTICLES WITH A MODIFIED BACULOVIRUS EXPRESSION SYSTEM | Deutsches Krebsforschungszentrum (DE) | 2012-02-08 | — | — | EP | disclosed |
| US-7964350-B1 | Sample preparation for in situ nucleic acid analysis | APPLIED BIOSYSTEMS, LLC (US) | 2011-06-21 | — | — | US | disclosed |
| WO-2010112533-A1 | ENHANCED PRODUCTION OF PAPILLOMAVIRUS-LIKE PARTICLES WITH A MODIFIED BACULOVIRUS EXPRESSION SYSTEM | DEUTSCHES KREBSFORSCHUNGSZENTRUM (DE) | 2010-10-07 | — | — | WO | disclosed |
| WO-2010097066-A1 | SERINE PROTEASE INHIBITORS FOR THE SPECIFIC INHIBITION OF TISSUE KALLIKREINS | UNIVERSITÄTSKLINIKUM SCHLESWIG-HOLSTEIN (DE) | 2010-09-02 | — | — | WO | disclosed |
| EP-1198256-A4 | PEPTIDE-LIPID CONJUGATES, LIPOSOMES AND LIPOSOMAL DRUG DELIVERY | LIPOSOME CORP (US) | 2004-06-16 | — | — | EP | disclosed |
| WO-2001000247-A9 | PEPTIDE-LIPID CONJUGATES, LIPOSOMES AND LIPOSOMAL DRUG DELIVERY | LIPOSOME CO INC (US) | 2002-08-29 | — | — | WO | disclosed |
| EP-1198256-A1 | PEPTIDE-LIPID CONJUGATES, LIPOSOMES AND LIPOSOMAL DRUG DELIVERY | THE LIPOSOME CORPORATION (US) | 2002-04-24 | — | — | EP | disclosed |
| WO-2001000247-A1 | PEPTIDE-LIPID CONJUGATES, LIPOSOMES AND LIPOSOMAL DRUG DELIVERY | THE LIPOSOME COMPANY, INC. (US) | 2001-01-04 | — | — | WO | disclosed |
| WO-1998034638-A1 | MASPIN INHIBITION OF TPA ACTIVITY | DANA-FARBER CANCER INSTITUTE (US) | 1998-08-13 | — | — | WO | disclosed |