Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRM6 | O15303 | 5/20 | 0.61 |
| ▸ | MAPT | P10636 | 9/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.51 |
| ▸ | HPGD | P15428 | 4/20 | 0.51 |
| ▸ | GAA | P10253 | 2/20 | 0.51 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.51 |
| ▸ | MEN1 | O00255 | 4/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.51 |
| ▸ | GPR55 | Q9Y2T6 | 2/20 | 0.49 |
| ▸ | POLB | P06746 | 2/20 | 0.49 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.48 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.47 |
| ▸ | ADORA1 | P30542 | 3/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.44 |
| ▸ | XBP1 | P17861 | 1/20 | 0.43 |
| ▸ | APP | P05067 | 1/20 | 0.43 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.43 |
| ▸ | CDC7 | O00311 | 1/20 | 0.42 |
| ▸ | DBF4 | Q9UBU7 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3980249 | 0.92 | GRM6 (0.73) | GRM6MAPTALDH1A1HPGDGAA | |
| SCHEMBL3974186 | 0.88 | GRM6 (0.61) | GRM6MAPTALDH1A1HPGDGAA | |
| SCHEMBL3974628 | 0.88 | GRM6 (0.61) | GRM6MAPTALDH1A1HPGDGAA | |
| SCHEMBL3975104 | 0.87 | GRM6 (0.60) | GRM6MAPTALDH1A1HPGDGAA | |
| SCHEMBL3981712 | 0.85 | GRM6 (0.57) | GRM6MAPTALDH1A1HPGDGAA | |
| SCHEMBL4087642 | 0.85 | GRM6 (0.57) | GRM6MAPTALDH1A1HPGDGAA | |
| SCHEMBL3974980 | 0.76 | ALDH1A1 (0.65) | MAPTALDH1A1HPGDGAAMEN1 | |
| SCHEMBL4090650 | 0.74 | ADORA1 (0.77) | GRM6MAPTALDH1A1MEN1KMT2A | |
| SCHEMBL4086503 | 0.74 | ADORA1 (0.72) | GRM6MAPTALDH1A1MEN1KMT2A | |
| SCHEMBL4076833 | 0.72 | ADORA1 (0.66) | GRM6MAPTALDH1A1MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009049362-A1 | A1 ADENOSINE RECEPTOR ALLOSTERIC ENHANCERS | MONASH UNIVERSITY (AU) | 2009-04-23 | — | — | WO | disclosed |