Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SRC | P12931 | 18/20 | 0.56 |
| ▸ | ABL1 | P00519 | 2/20 | 0.50 |
| ▸ | BCR | P11274 | 2/20 | 0.50 |
| ▸ | EGFR | P00533 | 2/20 | 0.49 |
| ▸ | ERBB2 | P04626 | 2/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4121723 | 0.83 | SRC (0.64) | SRCABL1BCR | |
| SCHEMBL7254581 | 0.71 | SRC (0.62) | SRCABL1BCREGFRERBB2 | |
| SCHEMBL5253791 | 0.70 | SRC (0.67) | SRCABL1BCREGFRERBB2 | |
| SCHEMBL5256712 | 0.69 | SRC (0.74) | SRCABL1BCR | |
| SCHEMBL6382448 | 0.69 | SRC (0.71) | SRCABL1BCREGFRERBB2 | |
| SCHEMBL6997301 | 0.69 | SRC (0.58) | SRCABL1BCREGFRERBB2 | |
| SCHEMBL5253283 | 0.68 | SRC (0.74) | SRCABL1BCREGFRERBB2 | |
| SCHEMBL6386795 | 0.68 | PDE4B (0.58) | SRCEGFRERBB2 | |
| SCHEMBL6380874 | 0.68 | EGFR (0.73) | EGFRERBB2 | |
| SCHEMBL6384191 | 0.68 | PDE4B (0.58) | SRCEGFRERBB2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1981505-A4 | PREPARATION OF 7-ALKENYL-3 QUINOLINECARBONITRILES VIA A PALLADIUM MEDIATED COUPLING REACTION | WYETH CORP (US) | 2009-05-13 | — | — | EP | disclosed |
| EP-1981505-A2 | PREPARATION OF 7-ALKENYL-3 QUINOLINECARBONITRILES VIA A PALLADIUM MEDIATED COUPLING REACTION | Wyeth a Corporation of the State of Delaware (US) | 2008-10-22 | — | — | EP | disclosed |
| WO-2007092153-A2 | PREPARATION OF 7-ALKENYL-3 QUINOLINECARBONITRILES VIA A PALLADIUM MEDIATED COUPLING REACTION | WYETH (US) | 2007-08-16 | — | — | WO | disclosed |