Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IDO1 | P14902 | 2/20 | 0.37 |
| ▸ | EZH2 | Q15910 | 17/20 | 0.35 |
| ▸ | JAK2 | O60674 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3974267 | 0.90 | DRD3 (0.33) | IDO1 | |
| SCHEMBL3973851 | 0.81 | OPRD1 (0.39) | IDO1EZH2JAK2 | |
| SCHEMBL2427668 | 0.71 | GABRP (0.47) | — | |
| SCHEMBL13280650 | 0.68 | EZH2 (0.60) | EZH2 | |
| SCHEMBL13468281 | 0.68 | EZH2 (0.60) | EZH2 | |
| SCHEMBL16398147 | 0.68 | EZH2 (0.60) | EZH2 | |
| SCHEMBL15710202 | 0.68 | EZH2 (0.60) | EZH2 | |
| SCHEMBL15700429 | 0.68 | EZH2 (0.60) | EZH2 | |
| SCHEMBL15700378 | 0.68 | EZH2 (0.60) | EZH2 | |
| SCHEMBL13280112 | 0.68 | EZH2 (0.53) | EZH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2074120-A1 | TROPANE COMPOUNDS | Exelixis, Inc. (US) | 2009-07-01 | — | — | EP | disclosed |
| WO-2009055077-A1 | TROPANE COMPOUNDS | EXELIXIS, INC. (US) | 2009-04-30 | — | — | WO | disclosed |