Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOB | P27338 | 6/20 | 0.63 |
| ▸ | CYP26B1 | Q9NR63 | 2/20 | 0.56 |
| ▸ | CYP26A1 | O43174 | 1/20 | 0.56 |
| ▸ | FFAR1 | O14842 | 2/20 | 0.48 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.46 |
| ▸ | ESR1 | P03372 | 1/20 | 0.45 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.45 |
| ▸ | MAOA | P21397 | 2/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | TP53 | P04637 | 1/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.42 |
| ▸ | CYP1A1 | P04798 | 1/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.42 |
| ▸ | FYN | P06241 | 1/20 | 0.42 |
| ▸ | MAPK3 | P27361 | 1/20 | 0.42 |
| ▸ | AHR | P35869 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3925092 | 0.84 | ESR1 (0.68) | MAOBCYP26B1CYP26A1FFAR1HIF1A | |
| SCHEMBL14840839 | 0.84 | HIF1A (0.49) | MAOBCYP26B1CYP26A1FFAR1HIF1A | |
| SCHEMBL25012028 | 0.83 | MAOB (0.51) | MAOBCYP26B1CYP26A1FFAR1HIF1A | |
| SCHEMBL4448303 | 0.81 | APP (0.61) | MAOBHIF1AMAOAKDM4EALDH1A1 | |
| SCHEMBL11827981 | 0.81 | MAOB (0.62) | MAOBMAOAKDM4EALDH1A1CYP3A4 | |
| SCHEMBL11614291 | 0.79 | MAOB (0.59) | MAOBCYP26B1CYP26A1MAOAKDM4E | |
| SCHEMBL12369509 | 0.79 | MAOB (0.67) | MAOBCYP26B1CYP26A1HIF1AESR1 | |
| SCHEMBL16843540 | 0.78 | PLA2G2A (0.68) | KDM4EALDH1A1TP53CYP3A4MAPT | |
| SCHEMBL3983367 | 0.77 | MAOB (1.00) | MAOBFFAR1ESR1ESR2MAOA | |
| SCHEMBL3626409 | 0.77 | MAOB (0.68) | MAOBFFAR1ESR1ESR2MAOA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110386909-B | Method for synthesizing benzofuran derivative through copper-free ligand-free palladium catalyst | 中国科学院青岛生物能源与过程研究所 | 2023-07-07 | — | — | CN | disclosed |
| CN-110386909-A | A method of benzofuran derivatives are synthesized by no copper catalysis of ligand-free palladium agent | 中国科学院青岛生物能源与过程研究所 | 2019-10-29 | — | — | CN | disclosed |
| US-7473786-B1 | Methods and systems for preparing fused heterocyclic compounds using copper(I) catalysts | UNIVERSITY OF MASSACHUSETTS (US) | 2009-01-06 | — | — | US | disclosed |
| US-7473786-B1 | Methods and systems for preparing fused heterocyclic compounds using copper(I) catalysts | UNIVERSITY OF MASSACHUSETTS (US) | 2009-01-06 | — | — | US | disclosed |
| US-7473786-B1 | Methods and systems for preparing fused heterocyclic compounds using copper(I) catalysts | UNIVERSITY OF MASSACHUSETTS (US) | 2009-01-06 | — | — | US | disclosed |