Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A2 | P23975 | 2/20 | 0.32 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.32 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3979978 | 0.79 | — | — | |
| SCHEMBL3301265 | 0.78 | SLC6A4 (0.34) | SLC6A2SLC6A4SLC6A3 | |
| SCHEMBL6118690 | 0.77 | SLC6A4 (0.45) | SLC6A2SLC6A4SLC6A3 | |
| SCHEMBL4660108 | 0.75 | SLC6A4 (0.42) | SLC6A2SLC6A4SLC6A3 | |
| Acetic Acid SCHEMBL7469412 | 0.75 | L3MBTL1 (0.34) | SLC6A2SLC6A4SLC6A3 | |
| SCHEMBL20674336 | 0.74 | SLC6A4 (0.35) | SLC6A2SLC6A4SLC6A3 | |
| SCHEMBL1871691 | 0.74 | CCR5 (0.39) | SLC6A2SLC6A4SLC6A3 | |
| SCHEMBL4658920 | 0.73 | SLC6A4 (0.36) | SLC6A2SLC6A4SLC6A3 | |
| SCHEMBL4913906 | 0.73 | SLC6A2 (0.42) | SLC6A2SLC6A4SLC6A3 | |
| SCHEMBL1920876 | 0.72 | SLC6A4 (0.34) | SLC6A2SLC6A4SLC6A3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2118092-A1 | NEW N, N'- 2,4-DIANILINOPYRIMIDINE DERIVATIVES, PREPARATION THEREOF AS DRUGS, PHARMACEUTICAL COMPOSITIONS ESSENTIALLY AS IKK INHIBITORS | Sanofi-Aventis (FR) | 2009-11-18 | — | — | EP | disclosed |
| WO-2009056693-A1 | NOVEL DERIVATIVES OF N, N'- 2, 4-DIANILINOPYRIMIDINES, PREPARATION THEREOF AS MEDICAMENTS PHARMACEUTICAL COMPOSITIONS AND IN PARTICULAR AS IKK INHIBITORS | SANOFI-AVENTIS (FR) | 2009-05-07 | — | — | WO | disclosed |
| WO-2008099073-A1 | N, N' -2, 4-DIANILINOPYRIMIDINES PREPARATION AND USE THEREOF AS IKK INHIBITORS PREPARATION AND TEH PHARMACUETICAL COMPOSITIONS THEREOF | SANOFI-AVENTIS (FR) | 2008-08-21 | — | — | WO | disclosed |