Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRIN1 | Q05586 | 2/20 | 0.35 |
| ▸ | GRIN2B | Q13224 | 2/20 | 0.35 |
| ▸ | THRA | P10827 | 12/20 | 0.34 |
| ▸ | THRB | P10828 | 12/20 | 0.34 |
| ▸ | PIN1 | Q13526 | 3/20 | 0.33 |
| ▸ | LDHA | P00338 | 1/20 | 0.32 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4299290 | 0.94 | THRA (0.36) | GRIN1GRIN2BTHRATHRB | |
| SCHEMBL3982088 | 0.93 | GRIN1 (0.33) | GRIN1GRIN2BTHRATHRBPIN1 | |
| SCHEMBL3981706 | 0.90 | THRA (0.39) | THRATHRBPIN1LDHA | |
| SCHEMBL3985944 | 0.90 | THRA (0.39) | THRATHRBPIN1LDHA | |
| SCHEMBL3981701 | 0.90 | THRA (0.39) | THRATHRBPIN1LDHA | |
| SCHEMBL4305207 | 0.80 | THRB (0.39) | THRATHRBPIN1LDHA | |
| SCHEMBL3980346 | 0.79 | PIN1 (0.33) | THRATHRBPIN1LDHA | |
| SCHEMBL3978770 | 0.79 | THRA (0.36) | THRATHRBPIN1 | |
| SCHEMBL4302453 | 0.79 | THRA (0.37) | THRATHRB | |
| SCHEMBL3979612 | 0.78 | THRA (0.40) | THRATHRB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2024336-A1 | NOVEL PHARMACEUTICAL COMPOSITIONS | KARO BIO AB (SE) | 2009-02-18 | — | — | EP | disclosed |
| WO-2007128492-A1 | NOVEL PHARMACEUTICAL COMPOSITIONS | KARO BIO AB (SE) | 2007-11-15 | — | — | WO | disclosed |