SCHEMBL398359

SCHEMBL398359

c1ccc(-c2nnc(-c3ccc(N(c4ccccc4)c4ccc(-n5c6ccccc6c6ccccc65)cc4)cc3)o2)cc1

nearest known ligand 0.46

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
NPC1 O15118 14/20 0.46
RAB9A P51151 14/20 0.46
SMN1; SMN2 Q16637 6/20 0.46
KDM4E B2RXH2 6/20 0.46
HPGD P15428 6/20 0.46
ALDH1A1 P00352 5/20 0.46
CYP1A2 P05177 1/20 0.46
CYP3A4 P08684 1/20 0.46
CYP2D6 P10635 1/20 0.46
ATM Q13315 1/20 0.45
L3MBTL1 Q9Y468 1/20 0.45
KMT2A Q03164 2/20 0.43
POLB P06746 1/20 0.43
NFKB1 P19838 1/20 0.43
NFKB2 Q00653 1/20 0.43
RELA Q04206 1/20 0.43
MEN1 O00255 1/20 0.43
HSD17B10 Q99714 2/20 0.42
GLA P06280 1/20 0.42
MAPT P10636 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14465396 0.99 NPC1 (0.45) NPC1RAB9ASMN1; SMN2KDM4EHPGD
SCHEMBL14466397 0.99 NPC1 (0.45) NPC1RAB9ASMN1; SMN2KDM4EHPGD
SCHEMBL14465393 0.99 NPC1 (0.45) NPC1RAB9ASMN1; SMN2KDM4EHPGD
SCHEMBL14489880 0.97 NPC1 (0.46) NPC1RAB9ASMN1; SMN2KDM4EHPGD
SCHEMBL14465692 0.93 NPC1 (0.41) NPC1RAB9ASMN1; SMN2KDM4EHPGD
SCHEMBL11987964 0.93 NPC1 (0.41) NPC1RAB9ASMN1; SMN2KDM4EHPGD
SCHEMBL14489870 0.93 NPC1 (0.41) NPC1RAB9ASMN1; SMN2KDM4EHPGD
SCHEMBL14466364 0.93 RAB9A (0.46) NPC1RAB9ASMN1; SMN2KDM4EHPGD
SCHEMBL14465519 0.92 NPC1 (0.52) NPC1RAB9ASMN1; SMN2KDM4EHPGD
SCHEMBL5428206 0.92 NPC1 (0.43) NPC1RAB9ASMN1; SMN2KDM4EHPGD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 258 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11980087-B2 Triarylamine derivative, light-emitting substance, light-emitting element, light-emitting device, and electronic device SEMICONDUCTOR ENERGY LABORATORY CO., LTD. (JP) 2024-05-07 US disclosed
US-20230301178-A1 Triarylamine Derivative, Light-Emitting Substance, Light-Emitting Element, Light-Emitting Device, and Electronic Device SEMICONDUCTOR ENERGY LABORATORY CO., LTD. (JP) 2023-09-21 US disclosed
US-20230301178-A1 Triarylamine Derivative, Light-Emitting Substance, Light-Emitting Element, Light-Emitting Device, and Electronic Device SEMICONDUCTOR ENERGY LABORATORY CO., LTD. (JP) 2023-09-21 US disclosed
US-20230301178-A1 Triarylamine Derivative, Light-Emitting Substance, Light-Emitting Element, Light-Emitting Device, and Electronic Device SEMICONDUCTOR ENERGY LABORATORY CO., LTD. (JP) 2023-09-21 US disclosed
US-11678568-B2 Triarylamine derivative, light-emitting substance, light-emitting element, light-emitting device, and electronic device SEMICONDUCTOR ENERGY LABORATORY CO., LTD. 2023-06-13 US disclosed
US-11678568-B2 Triarylamine derivative, light-emitting substance, light-emitting element, light-emitting device, and electronic device SEMICONDUCTOR ENERGY LABORATORY CO., LTD. 2023-06-13 US disclosed
US-11678568-B2 Triarylamine derivative, light-emitting substance, light-emitting element, light-emitting device, and electronic device SEMICONDUCTOR ENERGY LABORATORY CO., LTD. 2023-06-13 US disclosed
EP-2192633-B1 Light-emitting element, light-emitting device, lighting device, and electronic device SEMICONDUCTOR ENERGY LAB (JP) 2021-04-14 EP disclosed
EP-2192633-B1 Light-emitting element, light-emitting device, lighting device, and electronic device SEMICONDUCTOR ENERGY LAB (JP) 2021-04-14 EP disclosed
US-20210036226-A1 Triarylamine Derivative, Light-Emitting Substance, Light-Emitting Element, Light-Emitting Device, and Electronic Device SEMICONDUCTOR ENERGY LABORATORY CO., LTD. (JP) 2021-02-04 US disclosed
US-20070222376-A1 Light-emitting element, light-emitting device, and electronic device SEMICONDUCTOR ENERGY LABORATORY CO., LTD. (JP) 2007-09-27 US disclosed
US-20070222376-A1 Light-emitting element, light-emitting device, and electronic device SEMICONDUCTOR ENERGY LABORATORY CO., LTD. (JP) 2007-09-27 US disclosed
US-20070222376-A1 Light-emitting element, light-emitting device, and electronic device SEMICONDUCTOR ENERGY LABORATORY CO., LTD. (JP) 2007-09-27 US disclosed
US-20070215889-A1 Aromatic amine compound, and light-emitting element, light-emitting device, and electronic appliance using the aromatic amine compound SEMICONDUCTOR ENERGY LABORATORY CO., LTD. (JP) 2007-09-20 US disclosed
US-20070215889-A1 Aromatic amine compound, and light-emitting element, light-emitting device, and electronic appliance using the aromatic amine compound SEMICONDUCTOR ENERGY LABORATORY CO., LTD. (JP) 2007-09-20 US disclosed
US-20070215889-A1 Aromatic amine compound, and light-emitting element, light-emitting device, and electronic appliance using the aromatic amine compound SEMICONDUCTOR ENERGY LABORATORY CO., LTD. (JP) 2007-09-20 US disclosed
WO-2007074893-A1 OXADIAZOLE DERIVATIVE, AND LIGHT EMITTING ELEMENT, LIGHT EMITTING DEVICE, AND ELECTRONIC DEVICE USING THE OXADIAZOLE DERIVATIVE SEMICONDUCTOR ENERGY LABORATORY CO., LTD. (JP) 2007-07-05 WO disclosed
US-20070149784-A1 Oxadiazole derivative, and light emitting element, light emitting device, and electronic device using the oxadiazole derivative SEMICONDUCTOR ENERGY LABORATORY CO., LTD. 2007-06-28 US disclosed
US-20070149784-A1 Oxadiazole derivative, and light emitting element, light emitting device, and electronic device using the oxadiazole derivative SEMICONDUCTOR ENERGY LABORATORY CO., LTD. 2007-06-28 US disclosed
US-20070149784-A1 Oxadiazole derivative, and light emitting element, light emitting device, and electronic device using the oxadiazole derivative SEMICONDUCTOR ENERGY LABORATORY CO., LTD. 2007-06-28 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20070149784-A1 Oxadiazole derivative, and light emitting element, light emitting device, and electronic device using the oxadiazole derivative OXA1L, ADRA1D, CRY1 NPC1 4535/4885RAB9A 3546/4885SMN1; SMN2 2738/4885
US-20230301178-A1 Triarylamine Derivative, Light-Emitting Substance, Light-Emitting Element, Light-Emitting Device, and Electronic Device AHR, NAT1, TAAR1 NPC1 2158/4885RAB9A 1181/4885SMN1; SMN2 4551/4885
US-20210036226-A1 Triarylamine Derivative, Light-Emitting Substance, Light-Emitting Element, Light-Emitting Device, and Electronic Device AHR, NAT1, TAAR1 NPC1 2158/4885RAB9A 1181/4885SMN1; SMN2 4551/4885
US-11678568-B2 Triarylamine derivative, light-emitting substance, light-emitting element, light-emitting device, and electronic device AHR, NAT1, TAAR1 NPC1 2158/4885RAB9A 1181/4885SMN1; SMN2 4551/4885
US-11980087-B2 Triarylamine derivative, light-emitting substance, light-emitting element, light-emitting device, and electronic device AHR, NAT1, TAAR1 NPC1 2158/4885RAB9A 1181/4885SMN1; SMN2 4551/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.