Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FABP3 | P05413 | 1/20 | 0.54 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.53 |
| ▸ | NR5A2 | O00482 | 1/20 | 0.53 |
| ▸ | NR5A1 | Q13285 | 1/20 | 0.53 |
| ▸ | LMNA | P02545 | 1/20 | 0.53 |
| ▸ | ESR1 | P03372 | 1/20 | 0.53 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.53 |
| ▸ | CDC25A | P30304 | 1/20 | 0.53 |
| ▸ | AGTR1 | P30556 | 1/20 | 0.53 |
| ▸ | AKT1 | P31749 | 1/20 | 0.53 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.53 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.53 |
| ▸ | MAPT | P10636 | 1/20 | 0.51 |
| ▸ | DGKA | P23743 | 1/20 | 0.50 |
| ▸ | RECQL | P46063 | 1/20 | 0.49 |
| ▸ | PLA2G1B | P04054 | 1/20 | 0.47 |
| ▸ | PLA2G2A | P14555 | 1/20 | 0.47 |
| ▸ | PLA2G10 | O15496 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2638014 | 1.00 | FABP3 (0.54) | FABP3SMN1; SMN2NR5A2NR5A1LMNA | |
| SCHEMBL31432721 | 1.00 | FABP3 (0.54) | FABP3SMN1; SMN2NR5A2NR5A1LMNA | |
| SCHEMBL1768918 | 1.00 | FABP3 (0.54) | FABP3SMN1; SMN2NR5A2NR5A1LMNA | |
| SCHEMBL3182833 | 1.00 | FABP3 (0.54) | FABP3SMN1; SMN2NR5A2NR5A1LMNA | |
| SCHEMBL22721397 | 1.00 | FABP3 (0.54) | FABP3SMN1; SMN2NR5A2NR5A1LMNA | |
| SCHEMBL1341976 | 1.00 | FABP3 (0.54) | FABP3SMN1; SMN2NR5A2NR5A1LMNA | |
| SCHEMBL6666152 | 0.98 | FABP3 (0.52) | FABP3SMN1; SMN2NR5A2NR5A1LMNA | |
| SCHEMBL617162 | 0.92 | ALDH1A1 (0.53) | FABP3SMN1; SMN2NR5A2NR5A1 | |
| SCHEMBL1643923 | 0.87 | FABP3 (0.62) | FABP3SMN1; SMN2NR5A2NR5A1LMNA | |
| SCHEMBL5475892 | 0.87 | FABP3 (0.62) | FABP3SMN1; SMN2NR5A2NR5A1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009055788-A1 | PNEUMOREDUCTIVE THERAPY AND COMPOSITIONS USEFUL THEREIN | AERIS THERAPEUTICS, INC. (US) | 2009-04-30 | — | — | WO | disclosed |